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【科普】乳腺癌的治疗
乳腺癌新的药物治疗靶标
Author: Catherine Thompson
Publication Date: July 2006
Breast cancer is a complex heterogeneous disease characterised by uncontrolled growth and spread of abnormal cells. It is also very prevalent, with reports from the World Health Organization estimating that more than 1.2 million people will be diagnosed with breast cancer in 2005, worldwide. In the United States, breast cancer is the second most common cancer in women (following skin cancer) with 212,930 new cases estimated for 2004 and an associated 40,840 deaths. In Europe, approximately 200,000 women are diagnosed with breast cancer each year (41,000 in the UK). Consequently, breast cancer is a high-priority research area and is recognized as one of the most aggressively pursued diseases in the history of medicine.
乳腺癌是一种复杂的异质性疾病，其特点就是非正常细胞的无限制增生和扩散，它是一种常见的癌症，就世界卫生组织估计仅2005年世界范围内就有超过120万人被诊断患上了该病，在美国女性中，乳腺癌是仅次于皮肤癌的第二大癌症，据估计2004年就有212930名新病例，40840名患者死于该病。在欧洲，每年大约有20万妇女被诊断患有乳腺癌（其中英国有41000例），因此，乳腺癌是一个优先进行的研究领域，是公认的在医药史上最被积极推动的疾病之一。
Encouragingly, cancer drug therapy is in a time of major transition. This time has been described by Bristol Myers Squibb (New York, NY), as a “golden era,” where decades of cancer research are now being translated into development of next generation therapeutics. Current pharmaceutical pipelines are testimony to the intensity of breast cancer drug development with at least 50 investigational drugs and drug combinations in clinical development.
令人鼓舞的是,癌症药物疗法处于主要的过渡时期，迈尔斯.碧宝(纽约)将该时期形容为一个"黄金时期",几十年对癌症研究的发展正在逐步发展转化为下一代疗法.目前制药公司被证明有能力开发至少50种临床实验用药和药物联合用药能力
Breast cancer treatment generally comprises of combinations that include surgery, radiotherapy, hormonal therapy, and chemotherapy. Clinical pipelines now reflect the emergence of two additional new therapy classes, namely, “innovative therapy” and “immunotherapy”. Current treatment is dominated by hormone or endocrine therapy as approximately 70% of breast cancers are hormone-responsive. But early treatments from the new classes are now reaching the market and are set to revolutionise therapy.
乳癌的治疗通常包括下列方法及它们的组合，包括外科,放射、激素治疗、化学治疗.目前临床已经出现两个新疗法班,即"创新疗法"、"免疫疗法".目前主流的治疗方法是激素治疗或内分泌治疗，大约70%为乳癌患者的激素反应型的.但是早期治疗现正进入新的市场,并成为革命性的疗法.
非常不错， 支持。 如果能加入目前国内的主要治疗方式以及缺陷就更好了，你说呢？ [标签:content1][标签:content2]
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作者:admin@医学,生命科学 2011-08-22 17:22
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