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【社会人文】“天然”壮阳药：让癌症噩梦成真
WASHINGTON (Reuters) - Two men seeking to boost sexual performance and grow bigger muscles instead ended up with advanced prostate cancer after taking "herbal" supplements, U.S. doctors reported on Tuesday.
They said many supplements marketed as "safe" and "natural" could contain unknown and potentially dangerous ingredients, and noted that the U.S. Food and Drug Administration has little authority to regulate them.
"Physicians need to ask their patients not only about the prescription drugs they may be taking, but -- perhaps even more importantly -- about the over-the-counter drugs and supplements, which may have a profound impact on certain health conditions," Dr. Claus Roehrborn, chairman of urology at the University of Texas Southwestern medical school, said in a statement.
Roehrborn's team became concerned about what they call herbal/hormonal dietary supplements, or HHDSs, after two men developed aggressive and incurable prostate cancer within months of taking the same supplement.
They analyzed the product, which they did not name for legal reasons, and found it contained two hormones -- testosterone and estradiol. When they tested it on tumor cells in the lab, they found it fueled the growth of prostate cancer cells more potently than testosterone alone, they reported in the journal Clinical Cancer Research.
"We filed an adverse event report with the FDA who issued a warning letter. The manufacturer responded by removing this HHDS product from the market," the researchers wrote.
"Individuals use HHDS for self-improvement, failure or distrust of conventional medicine, and because they believe that, these natural products are safe and drug-free," they wrote.
The researchers searched Web sites promoting such products and found they promised "'fountain of youth,' maintenance of a 'youthful' heart, relief of stress, and improvements in mood disturbances, stamina, energy, strength and virility."
The patients, a 67-year-old white man and a 51-year-old black man, have both survived but have extensive cancer that has spread throughout their bodies.
"Unlike prescription and over-the-counter drugs, the law does not require nutritional supplements to undergo pre-market approval for safety and efficacy," the researchers wrote.
"The Dietary Supplement Health and Education Act in 1994 (DSHEA) allows HHDS manufacturers to assume the sole responsibility for ensuring the effectiveness and safety of their products. Thus, the current Food Drug Administration regulatory system provides little oversight or assurance that HHDS will have predictable pharmacological effects or even that product labels provide accurate information to consumers."
http://www.reuters.com/article/healthNews/idUSN1439907820080115 本人认领该文编译，48小时后未提交译文请其他站友自由认领 "Natural" supplements caused cancer in 2 men: study
研究发现：“天然”补品可引起肿瘤
WASHINGTON (Reuters) - Two men seeking to boost sexual performance and grow bigger muscles instead ended up with advanced prostate cancer after taking "herbal" supplements, U.S. doctors reported on Tuesday.
华盛顿（路透社） - 本周二，据美国医生报道，两名男性为了提高性能力、增加肌肉而服用草药补品，结果却患上了晚期前列腺癌。
They said many supplements marketed as "safe" and "natural" could contain unknown and potentially dangerous ingredients, and noted that the U.S. Food and Drug Administration has little authority to regulate them.
他们说许多打着“安全”和“天然”旗号的补品里可能含有一些未知的、具有危险性的成份，并且解释说美国食品药品监督管理局对此类产品无权管理。
"Physicians need to ask their patients not only about the prescription drugs they may be taking, but -- perhaps even more importantly -- about the over-the-counter drugs and supplements, which may have a profound impact on certain health conditions," Dr. Claus Roehrborn, chairman of urology at the University of Texas Southwestern medical school, said in a statement.
“医生们应当不仅只询问病人他们在服用什么处方药，还应该询问他们服用非处方药和补品的情况，而后者可能有着更重要的意义，因为它们可对人体健康产生巨大的影响。” Claus Roehrborn博士在一份声明中说，他是得克萨斯大学西南医学院的泌尿外科主任。
Roehrborn's team became concerned about what they call herbal/hormonal dietary supplements, or HHDSs, after two men developed aggressive and incurable prostate cancer within months of taking the same supplement.
Roehrborn团队是在两名男性因服用同样的补品数月而罹患侵袭性难治性前列腺癌后而对这一问题开始关注的，他们称之为草药/激素食补，简称HHDSs。
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作者:admin@医学,生命科学 2011-03-13 05:14
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