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【medical-news】川崎病---它将导致心脏哪些问题?

Kawasaki Disease
Introduction
Kawasaki disease is an acute childhood illness that is characterized by inflammation of the blood vessels. Early diagnosis and treatment are important to prevent possible damage to the coronary arteries, which supply oxygen to the heart muscle.

The classic symptoms of Kawasaki disease are listed below:
Fever lasting for at least 4 days
Red eyes (conjunctivitis), usually without drainage
Redness of the lips, throat, and tongue (strawberry tongue)
Redness and swelling of the hands and feet, followed later by peeling of skin on the fingers and toes
A rash
Swollen gland in the neck (usually 1 large) measuring at least 1.5 cm or larger

Although children with Kawasaki disease usually have fever plus 4 of the 5 signs listed above, some children have fewer symptoms (incomplete Kawasaki disease). If your child has a fever for 5 or more days with 2 or 3 of these classic symptoms, without another diagnosis, you should bring your child to the doctor or other healthcare provider. In addition to the signs listed above, children with Kawasaki disease are often very fussy or irritable. Vomiting, diarrhea, abdominal pain, respiratory symptoms such as cough, and joint pains are common in the days before diagnosis.

What Heart Problems Can Occur in Kawasaki Disease?
Inflammation in the walls of the coronary arteries can cause them to weaken. The weakened artery forms an aneurysm, which is a bubble-shaped (saccular) or cigar-shaped (fusiform) enlargement (Figure). Without timely treatment, 1 in 5 children with Kawasaki disease will develop coronary aneurysms. Treatment in the first 10 days of illness reduces the risk of aneurysm formation to less than 5%. Kawasaki disease can also cause inflammation of the heart muscle (myocarditis) and leakiness of heart valves, but these problems are almost always temporary.

circulation,2008.8.12.

Kawasaki Disease.pdf (284.1k) 本人已认领该文编译,若48小时未完成,请其他战友自由认领. Kawasaki Disease
川崎病
Introduction
Kawasaki disease is an acute childhood illness that is characterized by inflammation of the blood vessels. Early diagnosis and treatment are important to prevent possible damage to the coronary arteries, which supply oxygen to the heart muscle.
导言
川崎病是一种急性以血管炎症为特征的儿童疾病。早期诊断和早期治疗是非常必要的,这样才能避免冠状动脉损伤,保证心肌的供氧。
The classic symptoms of Kawasaki disease are listed below:
Fever lasting for at least 4 days
Red eyes (conjunctivitis), usually without drainage
Redness of the lips, throat, and tongue (strawberry tongue)
Redness and swelling of the hands and feet, followed later by peeling of skin on the fingers and toes
A rash
Swollen gland in the neck (usually 1 large) measuring at least 1.5 cm or larger
川崎病的典型的症状如下:
发热持续4天以上
红眼(结膜炎),通常没有分泌物
口唇充血,咽部充血,舌乳头充血(舌草莓)
手足水肿、红斑,随后指、趾皮肤蜕皮
皮疹
颈部腺体 川崎病
导言
川崎病是一种急性以血管炎症为特征的儿童疾病。早期诊断和早期治疗是非常必要的,这样才能避免冠状动脉损伤,保证心肌的供氧。

川崎病的典型的症状如下:
发热持续4天以上
红眼(结膜炎),通常没有分泌物
口唇充血,咽部充血,舌乳头充血(舌草莓)
手足水肿、红斑,随后指、趾皮肤蜕皮
皮疹
颈部腺体 川琦病又称婴儿急性热性皮肤粘膜淋巴结综合征,是一种以血管炎症为特征的儿童疾病,早期诊断及治疗对防止营养心机的冠脉血管的损伤至关重要。
以下是川琦病的典型症状:
持续发热至少4天;
红眼病(结膜炎)不伴流泪;
唇红、咽喉红、舌红(草莓舌);
手脚红肿,伴随指(趾)端脱屑;
皮疹;
颈部淋巴结肿胀≥1.5cm.
尽管患川琦病的儿童通常会出现发热加上以上列出的4、5个典型症状,许多儿童出现发热(不典型川琦病)。如果您的孩子出现5天以上的发热,并伴有2-3个这些典型的症状,又得不出其他诊断,应该带您的孩子去看医生或者去医疗机构就诊。除了上述症状之外,患川琦病的儿童较易出现烦躁和应激症状,呕吐、腹泻、腹痛、咳嗽等呼吸系统症状、关节痛等在发病初期也常见。
川琦病患者会出现什么心脏问题?
冠状动脉血管壁的炎症可以引起血管弹性的减弱,从而形成囊泡状或者纺锤状的动脉瘤,且逐渐增大。如果不经过及时的治疗,1/5的儿童川琦病患者会发展成冠状动脉瘤。发病前10天内得到有效治疗可以减少5%的冠状动脉瘤形成率。川琦病也可引起心肌炎及心脏瓣膜瘘这些严重的疾病。 [标签:content1][标签:content2]

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作者:admin@医学,生命科学    2011-03-11 17:14
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