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【medical-news】GENESIS研究：确定影响儿童肥胖的孕
Objective: To identify those perinatal parameters and characteristics predisposing children to an increased risk of overweight during infancy and preschool years.
Design: The analyses were performed using data from the Growth, Exercise and Nutrition Epidemiological Study In preSchoolers.
Subjects: A representative sample of 2374 Greek preschoolers 1–5 years old.
Measurements: Anthropometric data, such as body weight, recumbent length and standing height, were obtained by using standard procedures and measuring equipment. Structured interviews were conducted with both parents to collect information on anthropometric, demographic, medical and behavioral data. Finally, children's anthropometric data at birth, 6 and 12 months of age were recorded from their birth certificates and medical records.
Results: Children born large for gestational age were 4.59 and 2.19 times more likely for being overweight at 6 and 12 months of age, respectively, than children born appropriate for gestational age. On the other hand, children that were exclusively breastfed were 0.49 and 0.54 times less likely for being overweight at 6 and 12 months of age, respectively, than children that were exclusively formula fed. Furthermore, 3- to 5-year-old children born to mothers who were both active and passive smokers during pregnancy were 1.79 times more likely of being overweight compared to children born to nonsmoking mothers. Finally, having an overweight father significantly increased the likelihood of childhood overweight at 12 months, 1–3 and 3–5 years of age.
Conclusion: Our findings showed that some of the perinatal parameters and characteristics examined in the current study predict overweight at infancy, while others at preschool years. Priority should be given to size at birth, breastfeeding, maternal smoking during pregnancy and parental overweight, when developing public health strategies to reduce the prevalence of childhood overweight and related chronic disease later in life.
http://www.nature.com/ijo/journal/v32/n1/abs/0803764a.html 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 Perinatal predictors of overweight at infancy and preschool childhood: the GENESIS study
GENESIS研究：围产期导致婴儿及学龄前儿童肥胖因素。
Objective: To identify those perinatal parameters and characteristics predisposing children to an increased risk of overweight during infancy and preschool years.
目的：研究围产期的参数和特点，发现导致婴儿及学龄前儿童肥胖的危险因素。
Design: The analyses were performed using data from the Growth, Exercise and Nutrition Epidemiological Study In preSchoolers.
设计：对学前教育者收集的儿童关于生长、锻炼以及营养流行病学方面的资料进行分析。
Subjects: A representative sample of 2374 Greek preschoolers 1–5 years old.
研究对象：2374名希腊1-5岁学龄前儿童。
Measurements: Anthropometric data, such as body weight, recumbent length and standing height, were obtained by using standard procedures and measuring equipment. Structured interviews were conducted with both parents to collect information on anthropometric, demographic, medical and behavioral data. Finally, children's anthropometric data at birth, 6 and 12 months of age were recorded from their birth certificates and medical records.
方法：体重、身长、身高等生长数据通过标准化程序和器材进行测量。结构化面试通过父母双方对生长数据、人口统计学资料、医学以及行为学方面资料的收集。最终，儿童出生时、6个月、12个月生长数据记录在出生证和病例里面。
Results: Children born large for gestational age were 4.59 and 2.19 times more likely for being overweight at 6 and 12 months of age, respectively, than children born appropriate for gestational age. On the other hand, children that were exclusively breastfed were 0.49 and 0.54 times less likely for being overweight at 6 and 12 months of age, respectively, than children that were exclusively formula fed. Furthermore, 3- to 5-year-old children born to mothers who were both active and passive smokers during pregnancy were 1.79 times more likely of being overweight compared to children born to nonsmoking mothers. Finally, having an overweight father significantly increased the likelihood of childhood overweight at 12 months, 1–3 and 3–5 years of age.
结果：与适于胎龄儿相比，大于胎龄儿在6个月和12个月大小时肥胖的风险性分别为4.59和2.19倍。另一方面，完全母乳喂养儿在6个月和12个月大小时肥胖的风险性分别是人工喂养儿的0.49和0.54倍。此外，母亲在怀孕期间主动和被动吸烟的儿童在3—5岁发生肥胖是孕期不吸烟母亲儿童的1.79倍。最后，父亲肥胖的儿童在12个月、1—3岁、3—5岁易发生肥胖。
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作者:admin@医学,生命科学 2011-05-22 19:03
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