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美国研究称激素补充疗法可能会造成听力受损
已有研究显示，激素补充疗法（HRT）会增加罹患中风、心脏病和某些癌症的危险，甚至会导致早老性痴呆症（Alzheimer's disease）。现在研究人员于2月24日表示，这种疗法还可能会造成听力损伤。
一项小规模研究的结果显示，在听力测试中，接受HRT的女性比同龄同性别的人听力要差10～30%。不过此项研究的结果还需要进一步验证。
罗彻斯特大学医学中心（University of Rochester Medical Center）的弗里西纳（Robert Frisina）及其同仁对32名年龄在60至86岁、使用了HRT的女性进行了三种不同的听力测试，还对32名未使用HRT的妇女进行了对比测试。
接受HRT的一组总体上听力较差，尤其在复杂的情况下——比如在鸡尾酒会那样嘈杂的环境中，听清楚别人谈话的差异就更为明显。
“很有必要向女性发出警告：HRT可能具有另一项明显的副作用，”弗里西纳在一份声明中说。
“这些结果很让人吃惊。我们认为，激素可以帮助女性改善听力，因为耳朵里有雌激素的受体。但这结果和我们预想的相反。”
弗里西纳及其同事在佛罗里达州代顿纳（Daytona）举行的美国耳鼻喉科研究协会（Association for Research in Otolaryngology）会议上宣读了他们的论文。
Hormone therapy may affect hearing, study shows
Tue Feb 24, 2004 11:03 PM ET
WASHINGTON (Reuters) - Hormone replacement therapy, already blamed for raising the risk of stroke, heart attack, some kinds of cancer and even Alzheimer's disease, may also cause hearing loss, researchers said on Tuesday.
The study is a small one and will need to be verified, but it suggests that women taking HRT did anywhere from 10 to 30 percent worse on hearing tests than women of the same age not taking hormones.
Robert Frisina and colleagues at the University of Rochester Medical Center ran three different hearing tests on 32 women aged between 60 and 86 who took HRT and 32 who did not.
The HRT group heard more poorly in general but especially in complex situations such as understanding someone amid a loud backdrop like a cocktail party.
"It's important to alert women that there could be another significant side effect of hormone-replacement therapy," Frisina said in a statement.
"These results are very surprising. We thought hormones would help women hear better, because of the presence of estrogen receptors in the ear. This is the opposite of what we were expecting."
Frisina and colleagues presented their study at a meeting of the Association for Research in Otolaryngology in Daytona, Florida. [标签:content1][标签:content2]
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作者:admin@医学,生命科学 2011-05-02 05:14
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