主页 > 医学新闻 >
【medical-news】婴儿俯卧睡眠可能诱发猝死综合征
Prone Sleeping Impairs Circulatory Control During Sleep in Healthy Term Infants: Implications for SIDS
Stephanie R. Yiallourou, BSc Hons; Adrian M. Walker, PhD; Rosemary S. C. Horne, PhD Ritchie Centre for Baby Health Research, Monash Institute of Medical Research, Monash University, Melbourne, Victoria, Australia
Study Objectives:
To determine the effects of sleeping position on development of circulatory control in infants over the first 6 months of postnatal age (PNA).
Design:
Effects of sleeping position, sleep state and PNA on beat-beat heart rate (HR) and mean arterial pressure (MAP) responses to a headup tilt (HUT) were assessed during sleep in infants at 2-4 wks, 2-3 mo and 5-6 mo PNA.
Measurements:
Daytime polysomnography was performed on 20 fullterm infants (12 F/8 M) and MAP was recorded continuously and noninvasively (FinometerTM). HUTs of 15º were performed during active sleep (AS) and quiet sleep (QS) in both the prone and supine sleeping positions. MAP and HR data were expressed as the percentage change from baseline, and responses were divided into initial, middle and late phases.
Results:
In the supine position HUT usually resulted in an initial increase (P < 0.05) in HR and MAP, followed by decreases (P < 0.05) in HR and MAP in the middle phase; subsequently HR and MAP returned to baseline in the late phase. By contrast, in the prone position the initial HUT-induced rises in HR and MAP were usually absent, and at 2-3 mo MAP actually decreased (P < 0.05); subsequently HR but not MAP returned to baseline. At 2-3 mo, MAP was lower (P < 0.05) in prone than supine sleeping throughout the HUT.
Conclusions:
Prone sleeping alters MAP responses to a HUT during QS at 2-3 mo PNA. Decreased autonomic responsiveness may contribute to the increased risk for SIDS of infants sleeping in the prone position. [标签:content1][标签:content2]
阅读本文的人还阅读：
作者:admin@医学,生命科学 2011-05-05 17:49
医学,生命科学网