主页 > 医学讨论 >
【medical-news】新研究表明肥胖可能降低男性生育
NEW YORK (Reuters Health) - Being obese may dim a man's chances of becoming a father, even if he is otherwise healthy, a new study suggests.
Researchers found that among 87 healthy men ages 19 to 48, those who were obese were less likely to have ever fathered a child. More importantly, they showed hormonal differences that point to a reduced reproductive capacity, the researchers report in the journal Fertility and Sterility.
Compared with their thinner counterparts, obese men had lower levels of testosterone in their blood, as well as lower levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) -- both essential to reproduction.
According to the researchers, these relatively low levels of LH and FSH are suggestive of a "partial" hypogonadotropic hypogonadism. This is a condition in which the testes do not function properly due to signaling problems in the hypothalamus or pituitary gland, two brain structures involved in hormone secretion.
The findings suggest that obesity alone is an "infertility factor" in otherwise healthy men, write Dr. Eric M. Pauli and his colleagues at the Pennsylvania State University College of Medicine in Hershey.
Of the 87 men in the study, 68 percent had had a child. Pauli's team found that the average body mass index, or BMI, was lower among these men compared with those who'd never fathered a child; in the former group, the average BMI was 28, which falls into the range for "overweight," while the average BMI for childless men was nearly 32, which falls into the "obese" range.
When the researchers assessed the men for several reproductive hormones, they found that the more obese a man was, the lower was his LH and FSH levels. On the other hand, increasing obesity correlated with increasing estrogen levels.
Excess body fat, Pauli's team explains, may increase the conversion of testosterone to estrogen in a man's blood. Such hormone alterations could, in turn, signal the brain to suppress FSH and LH production.
Past studies have linked obesity with a dampened libido and increased risk of erectile dysfunction, the researchers note. Those effects, they say, along with the hormonal alterations seen in this study, could act together to decrease an obese man's fertility.
SOURCE: Fertility and Sterility, August 2008. 本人认领该文编译，若超过48小时未能交稿，请他人自由认领。 Obesity may diminish a man's fertility
肥胖症可能降低男性的生育能力
NEW YORK (Reuters Health) - Being obese may dim a man's chances of becoming a father, even if he is otherwise healthy, a new study suggests.
纽约（路透社 健康）-一项新报告指出：肥胖男士成为父亲的机会可能不高，即使他其他方面健康。
Researchers found that among 87 healthy men ages 19 to 48, those who were obese were less likely to have ever fathered a child. More importantly, they showed hormonal differences that point to a reduced reproductive capacity, the researchers report in the journal Fertility and Sterility.
研究人员在Fertility and Sterility中报道说，在他们调查的87个，年龄在19到48随范围内的健康男性中，发现那些肥胖的男性不容易成为孩子的父亲。更重要的是，肥胖男性显示出荷尔蒙的不同，这些差别可以表明生育能力的降低。
Compared with their thinner counterparts, obese men had lower levels of testosteroe
in their blood, as well as lower levels of luteinizing hormone (LH) and follicle-stimulating hormone (FSH) -- both essential to reproduction.
和瘦的受试者相比，肥胖男性血液中的睾酮水平较低，同时促黄体激素(LH)和促卵泡激素(FSH)的水平也较低，这两种激素对生育至关重要。
According to the researchers, these relatively low levels of LH and FSH are suggestive of a "partial" hypogonadotropic hypogonadism. This is a condition in which the testes do not function properly due to signaling problems in the hypothalamus or pituitary gland, two brain structures involved in hormone secretion.
据研究表明，那些相关的低水平的LH和FSH提示“局部”的低促性腺素性功能减退症。这种情况是由于能调节激素分泌的下丘脑或者脑垂体发出信号的问题，结果导致睾丸功能绪乱。
The findings suggest that obesity alone is an "infertility factor" in otherwise healthy men, write Dr. Eric M. Pauli and his colleagues at the Pennsylvania State University College of Medicine in Hershey.
研究发现在仅有肥胖症而其他方面的男性中，肥胖症是一个单独“不孕因素”，宾夕法尼亚大学医学部的Dr. Eric M. Pauli和他的同事这样写道
Of the 87 men in the study, 68 percent had had a child. Pauli's team found that the
average body mass index, or BMI, was lower among these men compared with those who'd never fathered a child; in the former group, the average BMI was 28, which falls into the range for "overweight," while the average BMI for childless
阅读本文的人还阅读：
作者:admin@医学,生命科学 2011-04-26 17:11
医学,生命科学网