主页 > 医学讨论 >

【科普】低剂量口服避孕药更能降低患卵巢癌的

Low-dose "Pill" reduces ovarian cancer risk
低剂量药丸降低患卵巢癌的风险
NEW YORK (Reuters Health) - Oral contraceptives with low levels of estrogen and progestin reduce the risk of ovarian cancer even more than older versions of the "Pill", according to investigators at the University of Hawaii in Honolulu.
据纽约(路透社健康频道)报道——檀香山的夏威夷大学研究者指出,低含量雌激素和黄体酮的口服避孕药比旧的药丸更能降低患卵巢癌的风险。
The benefits of oral contraceptive pills in protecting against ovarian cancer have long been recognized, Dr. Galina Lurie and her colleagues note in their report in the medical journal Obstetrics & Gynecology. However, over the last 30 years the doses of hormones in the pills have been decreased, to reduce side effects.
Galina Lurie博士和他的同事在发表在《产科与妇科》医学杂志的文章中提到,长期以来人们就意识到口服避孕药有益于预防卵巢癌。然而,持续30年来,这些避孕药片里的激素含量都不断降低以减少不良反应。

To see how this might have affected ovarian cancer risk, Lurie's group conducted a population-based study in Hawaii and Los Angeles involving 745 women diagnosed with ovarian cancer and a comparison group of 943 women matched by age and ethnicity and who were free of cancer.
为研究这些激素对卵巢癌症危险性有何影响,Lurie的研究组在夏威夷和洛杉矶开展了一个以群众为主的研究,该研究包括有745名卵巢癌患者的患者组和有943名健康的,并且年龄和人种都符合的对照组。
Health information was collected by standard questionnaires, and interviewers used photo albums to help participants identify the specific oral contraceptive pills they had used.
通过标准调查表来收集健康信息,调查人员使用各种药片的相片来让参试者确定她们使用的是何种口服避孕药。
Overall, women who had used any oral contraceptive had a 50 percent reduction in the risk of developing ovarian cancer than women who had never taken the Pill, the investigators report.
调查人员得出的总的数据显示,服用口服避孕药的女性患卵巢癌的几率比没有服药的低50%。
However, the risk was reduced by 38 percent for women who took high estrogen and high progestin pills, while the risk reduction was 81 percent for those taking pills with low levels of both hormones.
然而,服用雌激素和黄体酮含量高的药片的女性,这个降低的几率值为38%,服用激素含量低的药片的女性,这个值为81%。
"Up to 42 percent of ovarian cancers might have been avoided if all women used some form of combined oral contraceptive pills," Lurie and her associates calculate.
Furthermore, they say, "An estimated 73 percent of ovarian cancers might have been avoided if all women used oral contraceptive pill formulation of low estrogen and low progestin."
Lurie 和她的助手预测:“如果所有的女性都服用某种复合口服避孕药的话,避免患上卵巢癌的几率可能高达42%,并且,如果她们都服用服用雌激素和黄体酮含量低的药片的话,估计73%的卵巢癌可以避免”。

SOURCE: Obstetrics & Gynecology, March 2007.
来源:产科与妇科,2007年3月

~~~~~~~~~~~~~~~~~~~~~~~
编辑后
低剂量口服避孕药更能降低患卵巢癌的风险
据最新研究指出,服用雌激素和黄体酮含量低的口服避孕药比服用以往的药片更能降低患卵巢癌的风险。
檀香山的夏威夷大学研究者,Galina Lurie博士和同事在发表在《产科与妇科》医学杂志的文章中提到,长久以来人们就意识到口服避孕药有益于预防卵巢癌。然而,30年来,这些避孕药的激素含量都在不断降低以减少不良反应。
为研究这些激素对卵巢癌症危险性有何影响,Lurie的研究组在夏威夷和洛杉矶开展了一个以群众为主的研究,该研究包括有745名卵巢癌患者的患者组和有943名健康的,并且年龄和人种都符合要求的对照组。
调查人员通过标准调查表来收集健康信息,并使用药片的相片来让参试者确定她们服用的是何种口服避孕药。得出的数据显示,服用口服避孕药的女性患卵巢癌的几率比没有服药的低50%。然而,服用雌激素和黄体酮含量高的药片的女性,这个降低的几率值为38%,服用激素含量低的药片的女性,这个值为81%。
Lurie 和她的助手预测:“如果女性都服用某种复合口服避孕药的话,避免患上卵巢癌的几率可能高达42%,并且,如果她们都服用服用雌激素和黄体酮含量低的药片的话,估计73%的卵巢癌可以避免”。 Low-dose "Pill"还是译为”低剂量'药片' “吧,因为文章实际上是讲激素水平低。个人意见,仅供参考。 [标签:content1][标签:content2]

阅读本文的人还阅读:

【J Clin Oncol】使用调查问

急性心梗单支病变患者接

【medical-news】肝癌肝移植

【medical-news】舒张期心衰

【文摘发布】慢性肾脏病

作者:admin@医学,生命科学    2011-04-02 05:14
医学,生命科学网