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【medical-news】机体调节血糖机制的新发现
New Mechanism for Controlling Blood Sugar Level Discovered
ScienceDaily (Jan. 21, 2011) — Medical scientists at the University of Leicester have identified for the first time a new way in which our body controls the levels of sugar in our blood following a meal.
They have discovered the part played by a particular protein in helping to maintain correct blood sugar levels.
The breakthrough was made in the University of Leicester by a team led by Professor Andrew Tobin, Professor of Cell Biology, who is a Wellcome Trust Senior Research Fellow. The research is published online ahead of print in the international scientific journal the Proceedings of the National Academy of Sciences.
Professor Tobin said: "The work, which was done wholly at the University of Leicester, is focused on the mechanisms by which our bodies control the level of sugar in our blood following a meal.
"We found that in order to maintain the correct levels of sugar, a protein present on the cells that release insulin in the pancreas has to be active. This protein, called the M3-muscarinic receptor, is not only active but also needs to undergo a specific change. This change triggers insulin release and the control of blood sugar levels."
Professor Tobin added: "Without the change in the M3-muscarinic receptor protein sugar levels go up in the same way that we see in diabetes. We are of course testing if the mechanism of controlling sugar levels we have discovered is one of the mechanisms disrupted in diabetes. If this were the case then our studies would have important implications in diabetes."
The work was funded by the Wellcome Trust.
This hematoxylin- and eosin-stained pancreatic slice illustrates an islet of Langerhans adjacent to a capillary. (Credit: University of Leicester) 【medical-news】脂肪组织应激信号通路调控肝脏胰岛素抵抗 还...发表时间：2010-9-15回帖数：2如题,肯定翻译过程中有很多纰漏,望指正!附上原文和自己的翻译! 版主super19830102留... 但在fko小鼠中未发现.(图s6)两类小鼠中在机体糖酵解和糖原合成中无差别.(图2f,j).综上,...www.ruanjian520.com/thread-... - 2010-09-15-快照-【medical-news】脂肪组织应激信号通路调控肝脏胰岛素抵抗 还..." 医药新知_39健康问答_39健康网有时会引起危及生命的感染.美国科学家发现了使这种细菌变坏的一个“基因工具箱”. ... 这可能是由于负反馈调节使然——肥胖者吃得太多,以至于机体发出信号来下调ghrelin水平...ask.39.net/...tion/645046.html-2004-09-07-快照-医药新知_39健康问答_39健康网" 中国计量院计量科学咨询委员会成立文件类型:PDF/Adobe Acrobat- 文字版行分布处理、动态连接、自适应性、容错和自修复性等功能的机制,使信息系统走出 20 ... 4 个层次的重要 生命现象,应用于生物检测、良种培育、新药发现、疾病防治等领域,提升...lib.cjlu.edu.cn/...JCK0804.pdf-2011-01-06-科学咨询委员会成立"[标签:content2]
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作者:admin@医学,生命科学 2011-01-23 00:53
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