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【medical-news】细菌性肺炎患者心脏病风险增加
Bacterial pneumonia patients at increased risk of major heart problems
A new study suggests patients hospitalized with pneumonia may be at serious risk of new or worsening heart problems. The study is published in the July 15 issue of Clinical Infectious Diseases, currently available online.
Researchers led by Daniel Musher, MD, studied the records of all 170 patients hospitalized with pneumococcal pneumonia at a Texas Veterans Affairs medical center from 2001 to 2005. They found that 19.4 percent of them had a heart attack or other major heart problem concurrently at the time of admission, and that the presence of the heart condition significantly increased mortality from pneumonia.
In this study, the authors note, when adult patients were hospitalized with a diagnosis of bacterial pneumonia, “the concurrence of pneumonia and a new cardiac event was often unrecognized, especially in the first 12-24 hours of hospitalization, which led some patients to go without antibiotics for pneumonia and others to have no cardiac monitoring or anticoagulant therapy.”
The authors propose that pneumonia increases the risk of heart problems by increasing the heart’s demand for oxygen while simultaneously causing a decrease in the lungs’ ability to transfer oxygen from the air to the blood. Also, pneumonia raises blood levels of a type of a chemical signal called a cytokine that promotes the formation of blood clots and that decreases the efficiency of the heart.
“Physicians who take care of patients with pneumonia or with acute coronary syndromes need to be aware of the possible concurrence of the two diseases in an individual patient,” said Dr. Musher.
Fast Facts
Nearly 20 percent of patients admitted with pneumococcal pneumonia at a Texas Veterans Affairs medical center had a heart attack or other major heart problem concurrently at the time of admission, and the heart condition significantly increased mortality from pneumonia.
When patients were diagnosed with pneumonia, the heart problem frequently went unrecognized.
Physicians should be aware of the possibility that a patient has both conditions.
http://www.eurekalert.org/pub_releases/2007-06/idso-bpp061807.php 本人认领此文翻译，48小时后提交 Public release date: 18-Jun-2007
发表日期：2007年6月18日
Bacterial pneumonia patients at increased risk of major heart problems
细菌性肺炎患者心脏病风险增加
A new study suggests patients hospitalized with pneumonia may be at serious risk of new or worsening heart problems. The study is published in the July 15 issue of Clinical Infectious Diseases, currently available online.
一项新研究表明因细菌性肺炎住院的病人有很大的新发或加重心脏病的风险。该研究将发表于7月15日的《临川感染疾病》上，目前网络上已可阅读这篇文章。
Researchers led by Daniel Musher, MD, studied the records of all 170 patients hospitalized with pneumococcal pneumonia at a Texas Veterans Affairs medical center from 2001 to 2005. They found that 19.4 percent of them had a heart attack or other major heart problem concurrently at the time of admission, and that the presence of the heart condition significantly increased mortality from pneumonia.
由医学博士Daniel Musher领衔的研究团队对2001年到2005年间因患肺炎链球菌性肺炎而在Texas Veterans Affairs医学中心住院的17名病人的资料进行了研究。结果发现这些人中的19.4%在入院时有心脏病发作或患有其他的心脏疾病，心脏疾病的存在显著增加了这些病人的肺炎死亡率。
In this study, the authors note, when adult patients were hospitalized with a diagnosis of bacterial pneumonia, “the concurrence of pneumonia and a new cardiac event was often unrecognized, especially in the first 12-24 hours of hospitalization, which led some patients to go without antibiotics for pneumonia and others to have no cardiac monitoring or anticoagulant therapy.”
在这项研究中，研究者们注意到当成年病人被诊断为细菌性肺炎而住院时，“这种病人同时患有肺炎和新发的心脏疾病的情况并没有被认识到，尤其是在入院后的12到24小时内，这导致一些病人没有被及时给与抗生素治疗肺炎，另一些病人没有进行心脏监测或接受抗凝治疗。”
The authors propose that pneumonia increases the risk of heart problems by increasing the heart’s demand for oxygen while simultaneously causing a decrease in the lungs’ ability to transfer oxygen from the air to the blood. Also, pneumonia raises blood levels of a type of a chemical signal called a cytokine that promotes the formation of blood clots and that decreases the efficiency of the heart.
研究者们认为肺炎增加了发生心脏病的风险，因为肺炎增加了心脏的需氧量但同时又降低了肺脏的通气功能，使得入血的氧气量下降。而且，肺炎可升高一种称为细胞因子的化学信号的血液浓度，此化学因子可促进血栓形成并降低心脏工作效率。
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作者:admin@医学,生命科学 2011-03-10 05:11
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