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【Nature】肿瘤生物标记物带来的思考
Genomic technologies offer the promise of a comprehensive understanding of cancer. These technologies are being used to characterize tumours at the molecular level, and several clinical successes have shown that such information can guide the design of drugs targeted to a relevant molecule. One of the main barriers to further progress is identifying the biological indicators, or biomarkers, of cancer that predict who will benefit from a particular targeted therapy.
nature06913.pdf (320.96k) Genomic technologies offer the promise of a comprehensive understanding of cancer. These technologies are being used to characterize tumours at the molecular level, and several clinical successes have shown that such information can guide the design of drugs targeted to a relevant molecule. One of the main barriers to further progress is identifying the biological indicators, or biomarkers, of cancer that predict who will benefit from a particular targeted therapy.
基因组学技术为全面的了解肿瘤提供了希望。这些技术被用来在分子水平描述肿瘤的特征，许多在临床中的成功应用显示了这些信息能够指导设计靶向相关分子的药物。阻碍这项研究继续向前的主要障碍是，找到能够预示个体能够通过一个特别的靶向治疗能够受益，的肿瘤生物指示剂或者生物标记物。
基因组学技术为全面了解肿瘤提供了希望。它的相关技术可以在分子水平描述肿瘤的特征，临床中的许多成功病例显示了这些信息能够用于指导设计靶向相关分子的药物。这项研究进一步发展的主要障碍是识别肿瘤生物指示剂或者生物标记物，它们能够预测某个具体的靶向治疗能够对哪些人有效。 [标签:content1][标签:content2]
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作者:admin@医学,生命科学 2011-05-24 17:17
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