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【medical-news】指导纲要有助于鉴定儿童严重脑膜
Guidelines help identify serious meningitis cases in kids
Last Updated: Tuesday, January 2, 2007 | 5:01 PM ET
CBC News
Doctors have a faster way to determine if a child has a deadly type of meningitis, an inflammation of the membranes covering the brain and spinal cord.
It is relatively simple to treat viral meningitis, but the rare bacterial form that occurs in about one in 25 cases can be deadly. Patients must receive intravenous antibiotics as soon as they are admitted to hospital, said study author Dr. Lise Nigrovic of the Children's Hospital of Boston.
Many doctors start children on antibiotics while they wait for bacterial test results to show what kind of meningitis is causing the inflammation, but the results can take two to three days.
In Wednesday's Journal of the American Medical Association, Nigrovic and her colleagues report the results of their study on nearly 3,300 cases of meningitis in children who went to emergency departments between January 2001 and June 2004. Participants were between 29 days and 19 years of age.
"The absence of a seizure as well as defined blood and spinal fluid tests identified a low-risk group for bacterial meningitis," Nigrovic said. "And in that group, the risk of bacterial meningitis was one in a thousand."
The set of information they tested predicted which cases are likely not bacterial with 98 per cent accuracy.
Of the patients, 121, or 3.7 per cent, had bacterial meningitis and 3,174, or 96.3 per cent, had the nonbacterial form, the team found.
The findings could help to reduce unnecessary use of antibiotics, said Dr. Gary Fleisher, a pediatrician at the Children's Hospital of Boston, who was not part of the study.
As the test is adopted clinically, more research will show how the guidelines help in caring for children with bacterial meningitis, the researchers said.
In 2000, public health experts in the U.S. began recommending a vaccine to prevent bacterial meningitis in at-risk children younger than two. The incidence of bacterial meningitis has fallen since then, the team noted.
Health Canada approved a newer vaccine for bacterial 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 Guidelines help identify serious meningitis cases in kids
指导纲要有助于鉴定儿童严重脑脊膜炎
Last Updated: Tuesday, January 2, 2007 | 5:01 PM ET
最近更新：2007年1月2日，5：01pm
CBC News
CBC新闻
Doctors have a faster way to determine if a child has a deadly type of meningitis, an inflammation of the membranes covering the brain and spinal cord.
医生们发现一种快速诊断儿童是否罹患致死性的脑脊膜炎，是一种发生在大脑和脊髓表面被覆的膜的炎症。
It is relatively simple to treat viral meningitis, but the rare bacterial form that occurs in about one in 25 cases can be deadly. Patients must receive intravenous antibiotics as soon as they are admitted to hospital, said study author Dr. Lise Nigrovic of the Children's Hospital of Boston.
病毒性脑膜炎治疗上相对比较简单，但是大约细菌性脑膜炎中的4％的病例是致死性的。波士顿儿童医院的Dr. Lise Nigrovic说这种患者进入医院后，必须立即静脉内使用抗生素。
Many doctors start children on antibiotics while they wait for bacterial test results to show what kind of meningitis is causing the inflammation, but the results can take two to three days.
很多医生会等待患儿细菌检查的结果，确认是那种细菌导致脑膜炎，才开始应用抗生素但是，等待结果需要花费2－3天时间。
In Wednesday's Journal of the American Medical Association, Nigrovic and her colleagues report the results of their study on nearly 3,300 cases of meningitis in children who went to emergency departments between January 2001 and June 2004. Participants were between 29 days and 19 years of age.
Nigrovic和同事对在2001年1月至2004年1月间在急诊室就诊的约3300名脑膜炎患儿进行了研究，结果发表于周四出版的《美国医学会杂志》。患儿的平均年龄29天至19岁。
"The absence of a seizure as well as defined blood and spinal fluid tests identified a low-risk group for bacterial meningitis," Nigrovic said. "And in that group, the risk of bacterial meningitis was one in a thousand."
Nigrovic认为“血液和脑脊液检查结果一致，表明细菌性脑膜炎的发生属于低危险性的。在本研究的病例中细菌性脑膜炎的发生率是千分之一。”
The set of information they tested predicted which cases are likely not bacterial with 98 per cent accuracy.
他们体检后预测非细菌性脑膜炎的发生率是98％，基本准确。
Of the patients, 121, or 3.7 per cent, had bacterial meningitis and 3,174, or 96.3 per cent, had the nonbacterial form, the team found.
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作者:admin@医学,生命科学 2011-03-12 23:55
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