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【medical-news】最新研究表明：普通儿童肺炎不必
Science Daily — Children suffering from pneumonia could be spared the pain of the doctor's needle, thanks to new research funded by the British Lung Foundation.
The study, a world-first carried out by researchers at The University of Nottingham, discovered that children given oral treatment recovered as quickly, suffered less pain, required less oxygen therapy in hospital and were able to go home sooner than those given injections.
Two-and-a-half million children are affected by pneumonia each year in Europe. Until now, most children have been admitted to hospital and treated with injected antibiotics.
The findings suggest that these injections — endured by generations of children — may be unnecessary and could be replaced with oral doses of the medicine in the majority of cases. The study has been published online in the medical journal Thorax.
The research involved 243 children in hospitals throughout the UK. It was led by Terence Stephenson, Professor of Child Health, and Dr Maria Atkinson, both of The University of Nottingham's Medical School.
The study is the first in the developed world to compare oral treatment versus intravenous (IV) treatment for children with community-acquired pneumonia, who are unwell enough to need admission to hospital.
Professor Stephenson said: “This is good news for children who hate injections; good news for parents whose children will spend less time in hospital; good news for paediatricians who hate sticking needles in children and good news for the NHS, as fewer beds will be occupied and the treatment is cheaper.”
Dame Helena Shovelton, Chief Executive of the British Lung Foundation, said: “Treating childhood pneumonia will be less painful and distressing for parents, for children and for the health professionals caring for them, thanks to this research. We are very proud to have made this breakthrough possible.”
The research project involved 243 children, enrolled over a 21-month period at eight UK hospitals. Half were randomly assigned to receive a week of oral antibiotic treatment and half to receive antibiotics intravenously.
Follow-up over subsequent weeks showed that both types of treatment are effective in tackling the illness — and the former actually had a number of advantages over the latter. Oral antibiotics are also cheaper than those given via the IV route.
The researchers concluded: “We suggest that in countries like the UK, all but the sickest children with community-acquired pneumonia should be treated with oral amoxicillin initially.
“We expect that the majority of children will still require hospital admission but for a shorter period, to ensure oral medication is tolerated, and temperature and respiratory distress are settling. Most importantly children will be spared the pain and distress that injections cause.” 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 New Research Spares Children The Pain Of The Needle
新研究可使儿童免受针扎之苦
最新研究表明：普通儿童肺炎不必静脉抗生素，口服即可效果相当，甚至更好
Science Daily — Children suffering from pneumonia could be spared the pain of the doctor's needle, thanks to new research funded by the British Lung Foundation.
每日科学—据英国肺脏基金会资助的一项新研究报道，患肺炎的儿童可免受医生的针扎之苦。
The study, a world-first carried out by researchers at The University of Nottingham, discovered that children given oral treatment recovered as quickly, suffered less pain, required less oxygen therapy in hospital and were able to go home sooner than those given injections.
由诺丁汉大学的研究人员开展的这一研究在世界上尚属首次，他们发现与那些接受注射药物治疗的儿童相比，给与口服药进行治疗的儿童恢复的一样快，并且遭受的痛苦更少，住院期间需要氧疗的时间更短，能更早出院回家。
Two-and-a-half million children are affected by pneumonia each year in Europe. Until now, most children have been admitted to hospital and treated with injected antibiotics.
在欧洲，每年有二百五十万的儿童患有肺炎。目前为止，大多数儿童都被收治入院接受抗生素注射治疗。
The findings suggest that these injections — endured by generations of children — may be unnecessary and could be replaced with oral doses of the medicine in the majority of cases. The study has been published online in the medical journal Thorax.
该研究结果提示对于大多数病例，这些已在数代儿童身上使用的注射抗生素也许并不必要并可用口服药物代替。这一研究已发表在医学杂志《Thorax》的网络版上。
The research involved 243 children in hospitals throughout the UK. It was led by Terence Stephenson, Professor of Child Health, and Dr Maria Atkinson, both of The University of Nottingham's Medical School.
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作者:admin@医学,生命科学 2011-02-25 17:11
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