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【medical-news】不吸烟女性较不吸烟男性更易发生
About 20% of lung cancercancer cases in women occur in nonsmokers, the research suggests. In men, the percentage is about 8%.
To put the risk in perspective, a woman with no history of smoking has the same risk of developing lung cancer as she has of developing cervical cancercervical cancer, says lead researcher Heather Wakelee, MD, of Stanford University School of Medicine.
"People who have never smoked really do represent a substantial minority of lung cancer patients," Wakelee tells WebMD. "We need to be working now to better understand why these cancers occur."
In the Spotlight
The death of actress and activist Dana Reeve last March put the issue into the spotlight. Reeve was never a smoker, and her battle with lung cancer made millions of people aware for the first time that nonsmokers get the disease.
It has been believed that between 10% and 15% of lung cancer cases occur in people with no smoking history, but Wakelee says there has been little hard data to back up the figure.
"That is one of the main reasons we did this study," she says.
Wakelee and colleagues from Stanford and the Northern California Cancer Center tracked lung cancer incidence and deaths in more than 1 million people between ages 40 and 79 and living in the United States or Sweden.
They then calculated lung cancer cases in terms of new cases per person-year.
The researchers noted that age-adjusted lung cancer rates among current smokers are roughly 12 to 30 times higher than rates in people who never smoked.
But if the numbers are representative of the overall U.S. population, the inference is that about 8% of lung cancer cases in men and 20% of cases in women are among never-smokers, study co-author Ellen T. Chang, ScD, tells WebMD.
The study is published in the Feb. 10 issue of the Journal of Clinical Oncology.
Why Do Nonsmokers Get Lung Cancer?
It is still not clear if the lung cancer rate among never-smokers is growing or if the disease is as deadly in never-smokers.
And though there are many theories about why nonsmokers get lung cancer, little research has been done on the subject.
Air pollution, exposure to radon, and occupational exposure to asbestos have all been implicated in lung cancer risk. But most experts suspect that secondhand cigarette smoke exposure is the biggest risk factor for lung cancer among people who have never smoked.
"In this country, more women who don't smoke probably live with men who smoke than the other way around," the American Lung Association's chief medical officer, Norman Edelman, MD, tells WebMD.
"If you have a spouse who smokes, it is not only good for their health if they quit smokingquit smoking, it is good for yours," Edelman says. 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领 不吸烟女性较不吸烟男性更易发生肺癌
Feb. 9, 2007 -- Lung cancerLung cancer is not solely a smoker's disease -- and women who have never smoked are more at risk than men, new research confirms.
2007年2月9日消息-新的研究显示：肺癌不仅仅是吸烟者易患的疾病，从不吸烟的妇女比不吸烟男性更易发生肺癌。
About 20% of lung cancercancer cases in women occur in nonsmokers, the research suggests. In men, the percentage is about 8%.
不吸烟女性的肺癌发生率为20%，而不吸烟男性的肺癌发生率仅为8%。
To put the risk in perspective, a woman with no history of smoking has the same risk of developing lung cancer as she has of developing cervical cancercervical cancer, says lead researcher Heather Wakelee, MD, of Stanford University School of Medicine.
斯坦福大学医学院的Heather Wakelee博士说，“单从患病风险性角度来看，没有吸烟史的妇女患肺癌和患宫颈癌的几率相同。”
"People who have never smoked really do represent a substantial minority of lung cancer patients," Wakelee tells WebMD. "We need to be working now to better understand why these cancers occur."
“从不吸烟者在肺癌患者中基本占少数，我们需要进一步研究这些人患癌的机理。”
In the Spotlight
热点透视：
The death of actress and activist Dana Reeve last March put the issue into the spotlight. Reeve was never a smoker, and her battle with lung cancer made millions of people aware for the first time that nonsmokers get the disease.
去年3月电影演员和活动家Dana Reeve之死使这个话题成为热点。Reeve从不吸烟，但是关于她抗癌的报道使更多的人首次意识到非吸烟者也可以患肺癌。
It has been believed that between 10% and 15% of lung cancer cases occur in people with no smoking history, but Wakelee says there has been little hard data to back up the figure.
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作者:admin@医学,生命科学 2011-02-28 05:14
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