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【medical-news】生活方式与乳腺癌患者生存
(WebMD) Regular exercise combined with a healthy diet dramatically improves survival in breast cancer patients with early-stage disease, new research suggests.
Women in the study who ate the recommended five servings or more a day of vegetables and fruits and exercised moderately cut their risk of death in half, according to the study authors.
The benefits were seen both in obese and normal-weight women.
Moderate exercise was defined as the equivalent of taking a brisk, 30-minute walk a day, six days a week.
“Even in the women who were overweight, the combination of a fruit and vegetable-based diet and exercise lowered their risk of dying from breast cancer by 50 percent,” researcher John Pierce, PhD, tells WebMD.
Combination Was Key
Studies examining the impact of diet or exercise on breast cancer survival have been mixed, with some suggesting a benefit and others finding little evidence of an association.
Three to five hours of moderate exercise a week were was associated with a 50 percent reduction in the risk of dying from breast cancer in a study from Harvard Medical School, reported in 2005.
The new study by Pierce and colleagues from the University of California, San Diego, is the first to look at the combination of physical activity and diet on breast cancer survival.
The study included 1,490 women with early-stage breast cancer who were participants in a larger trial examining diet and breast cancer survival.
None of the women were told what to eat or how much to exercise, but they all were interviewed about their diets and physical activity levels when they entered the study between 1991 and 2000.
They were then followed for an average of 6.7 years.
About half as many obese women as lower-weight women reported eating five or more servings a day of fruits and vegetables and exercising regularly (16 percent vs. 30 percent).
But regardless of weight, women who ate the healthiest diets and exercised the most had roughly half as many breast cancer-related deaths during the follow-up period as the rest of the study population, including women who ate healthy diets but did not exercise regularly and women who exercised but didn’t eat five or more servings of fruits and vegetables a day.
The study appears in the June 10 issue of the Journal of Clinical Oncology.
Spotlight On Lifestyle
While a 50 percent risk reduction sounds impressive, American Cancer Society spokeswoman Debbie Saslow, PhD, points out a woman’s risk of dying from early-stage breast cancer is already very low.
The estimated 10-year mortality rate for the women in the trial who combined regular exercise with healthy diet was 7 percent, compared with roughly twice that for the rest of the study population.
She adds that the study joins a growing body of research suggesting that lifestyle plays an important role in breast cancer.
While there remain many unanswered questions about the impact of diet and exercise on breast cancer, Saslow says breast cancer survivors and women worried about getting the disease shouldn’t wait to adopt a healthy lifestyle.
“Whether a woman has had breast cancer or not, she should be exercising and eating right,” Saslow says.
Pierce and colleagues hope to follow up the study with an intervention trial designed to directly measure the impact of diet and exercise on breast cancer mortality.
By Salynn Boyles 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 Lifestyle And Breast Cancer Survival
生活方式与乳腺癌患者生存率的关系
(WebMD) Regular exercise combined with a healthy diet dramatically improves survival in breast cancer patients with early-stage disease, new research suggests.
(WebMD报道)新研究发现：经常进行体育锻炼并结合健康的饮食习惯能大幅度提高早期乳腺癌患者的生存率。
Women in the study who ate the recommended five servings or more a day of vegetables and fruits and exercised moderately cut their risk of death in half, according to the study authors.
该研究的作者说：研究中每日食用推荐的五种或更多的蔬菜水果并进行适度体育锻炼的女性的死亡风险下降百分之五十。
The benefits were seen both in obese and normal-weight women.
这一结果在肥胖与正常体重的女性中均可观察到。
Moderate exercise was defined as the equivalent of taking a brisk, 30-minute walk a day, six days a week.
适度体育锻炼的定义是运动量相当于每周六天、每天三十分钟的快步行走。
“Even in the women who were overweight, the combination of a fruit and vegetable-based diet and exercise lowered their risk of dying from breast cancer by 50 percent,” researcher John Pierce, PhD, tells WebMD.
“即使对于体重超重的女性，以水果蔬菜为基础的饮食结合体育锻炼也能使她们死于乳腺癌的风险下降百分之五十。”研究者John Pierce博士告诉WebMD说。
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作者:admin@医学,生命科学 2011-03-26 05:11
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