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阿司匹林可预防服用烟酸所引起的脸红

Don't Be Taken in by No-Flush Niacin

Posted by Simeon Margolis, M.D., Ph.D.
on Thu, Mar 15, 2007, 4:23 pm PDT

Now that statins have proven to be so effective in lowering blood levels of harmful LDL cholesterol, more and more attention is being directed at raising levels of protective HDL cholesterol.

Vitamin B3, or niacin, is the most effective drug for raising HDL cholesterol, and it also lowers LDL cholesterol and triglycerides. Several types of niacin preparations are available, but the best choice is the prescription drug Niaspan.

Niaspan is taken only at bedtime, unlike crystalline niacin products, which must be taken three times a day. Niaspan is also associated with fewer side effects, especially the troublesome flushing that frequently occurs shortly after taking a dose of niacin.

Even Niaspan, however, can cause flushing, and so people may be tempted to buy products advertised as “no-flush” niacin. These advertisers are correct: Their products do not cause flushing. What they fail to mention though is that their no-flush niacins don’t work. That is, they do not raise HDL cholesterol or lower LDL cholesterol or triglycerides.

If you are troubled by niacin-induced flushing, you can usually prevent it by taking one adult tablet of regular aspirin about 30 minutes before the niacin dose.

Niacin can be purchased over the counter, but you should only take this drug under the supervision of a physician because it can cause adverse effects much more serious than flushing, such as gout and damage to the liver and stomach.

A physician must be involved to make certain you do not take niacin if you are at increased risk for these harmful effects. Your doctor can also provide regular monitoring for early evidence of their possible development. 本人已认领该文编译,48小时后若未提交译文,请其他战友自由认领。 Don't Be Taken in by No-Flush Niacin
不要被宣称不会导致脸红的“烟酸”所骗
Posted by Simeon Margolis, M.D., Ph.D.
on Thu, Mar 15, 2007, 4:23 pm PDT
作者:医学和哲学双博士Simeon Margolis,
星期四,2007-3-15,4:23 pm太平洋夏令时
Now that statins have proven to be so effective in lowering blood levels of harmful LDL cholesterol, more and more attention is being directed at raising levels of protective HDL cholesterol.
既然他汀类药物已经被证明在降低血液中的有害的低密度脂蛋白胆固醇水平方面非常有效,所以越来越多的注意力集中在提高保护性的高密度脂蛋白胆固醇的水平上。
Vitamin B3, or niacin, is the most effective drug for raising HDL cholesterol, and it also lowers LDL cholesterol and triglycerides. Several types of niacin preparations are available, but the best choice is the prescription drug Niaspan.
维生素B3,或烟酸,是提高高密度脂蛋白胆固醇的最有效的药物,而它同时也降低了低密度脂蛋白胆固醇和甘油三酯。现在已经有好几种类型的烟酸制剂上市了,但是最佳的选择还是处方药物烟酸缓释片Niaspan。
Niaspan is taken only at bedtime, unlike crystalline niacin products, which must be taken three times a day. Niaspan is also associated with fewer side effects, especially the troublesome flushing that frequently occurs shortly after taking a dose of niacin.
Niaspan仅需要在睡前服用,并不像晶体烟酸制剂必须一天服用三次。Niaspan同时也有着更少的副作用,特别是令人讨厌的脸红,而它却在服用完烟酸后经常出现。
Even Niaspan, however, can cause flushing, and so people may be tempted to buy products advertised as “no-flush” niacin. These advertisers are correct: Their products do not cause flushing. What they fail to mention though is that their no-flush niacins don’t work. That is, they do not raise HDL cholesterol or lower LDL cholesterol or triglycerides.
即使是Niaspan也会导致脸红,所以人们被那些广告所宣称的“不会导致脸红的”烟酸所诱惑。这些广告者其实没说谎:他们的产品的确不会导致脸红。但是他们没有提到的是这种不会导致脸红的烟酸完全不起作用。也就是说,这种药物不会升高高密度脂蛋白胆固醇或降低低密度脂蛋白胆固醇或甘油三酯。
If you are troubled by niacin-induced flushing, you can usually prevent it by taking one adult tablet of regular aspirin about 30 minutes before the niacin dose.
如果你被烟酸所致的脸红所困扰,你可以通过在服用烟酸半小时前吃一片成人剂量的普通阿司匹林来预防它。
Niacin can be purchased over the counter, but you should only take this drug under the supervision of a physician because it can cause adverse effects much more serious than flushing, such as gout and damage to the liver and stomach.
烟酸不用处方就可以购买,但是你必须在一位医师的监督下服用这种药物,因为它会导致比脸红更严重的副作用,例如痛风,肝脏和胃的损伤。

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作者:admin@医学,生命科学    2011-02-07 05:14
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