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【medical-news】慢性呼吸衰竭COPD患者健康相关的生

Health-related quality of life in COPD patients with chronic respiratory failure
The Maugeri Respiratory Failure (MRF-28) and Severe Respiratory Insufficiency (SRI) questionnaires were recently developed to assess health-related quality of life (HRQoL) in patients with chronic respiratory failure, although not exclusively in chronic obstructive pulmonary disease (COPD) patients. The aim of the present study was to investigate whether the MRF-28 and SRI are reliable and valid HRQoL questionnaires in COPD patients with chronic hypercapnic respiratory failure (CHRF).
In total, 72 COPD patients with CHRF underwent pulmonary function and exercise testing, and completed the MRF-28, the SRI, the Chronic Respiratory Questionnaire (CRQ), the Hospital Anxiety and Depression Scale, the Groningen Activity and Restriction Scale and two dyspnoea indexes.
Physical domain scores of the questionnaires correlated with exercise tolerance, dyspnoea and daily activities, while psychological domains correlated strongly with anxiety and depression. Anxiety scores accounted for 51 and 56% of the total explained variance in total CRQ and SRI scores, respectively. The emphasis of the MRF-28 was restrictions in activities of daily living (52% of total variance).
In conclusion, the present study showed that the Maugeri Respiratory Failure and Severe Respiratory Insufficiency questionnaires were reliable and valid questionnaires in chronic obstructive pulmonary disease patients with chronic hypercapnic respiratory failure. While the emphasis in the Maugeri Respiratory Failure questionnaire is on activities of daily living, the Severe Respiratory Insufficiency questionnaire, like the Chronic Respiratory Questionnaire, is more related to anxiety and depression.
Eur Respir J 2008; 32:379-386 本人已认领该文编译,48小时后若未提交译文,请其他战友自由认领。 Health-related quality of life in COPD patients with chronic respiratory failure
COPD慢性呼衰患者健康相关的生活质量
The Maugeri Respiratory Failure (MRF-28) and Severe Respiratory Insufficiency (SRI) questionnaires were recently developed to assess health-related quality of life (HRQoL) in patients with chronic respiratory failure, although not exclusively in chronic obstructive pulmonary disease (COPD) patients.
Mauger呼吸衰竭(MRF-28)和严重呼吸功能不全问卷 (SRI)近期被完善以用于评价慢性呼衰患者的健康相关生活质量(HRQoL),而不是仅限于慢性阻塞性肺疾病(COPD)患者。
The aim of the present study was to investigate whether the MRF-28 and SRI are reliable and valid HRQoL questionnaires in COPD patients with chronic hypercapnic respiratory failure (CHRF).
当前研究目的在于明确MRF-28 和 SRI 是不是评估伴随有慢性高碳酸血症型呼衰(CHRF)的COPD患者HRQoL 的可信、有效的问卷。
In total, 72 COPD patients with CHRF underwent pulmonary function and exercise testing, and completed the MRF-28, the SRI, the Chronic Respiratory Questionnaire (CRQ), the Hospital Anxiety and Depression Scale, the Groningen Activity and Restriction Scale and two dyspnoea indexes.
共有72名伴有CHRF的COPD患者进行了肺功能检查和运动试验,完成了MRF-28、SRI、慢性呼吸系统问卷(CRQ)、医院焦虑抑郁量表、Groningen活性及限制性标尺以及两个呼吸困难指数的调查。
Physical domain scores of the questionnaires correlated with exercise tolerance, dyspnoea and daily activities, while psychological domains correlated strongly with anxiety and depression.
问卷中体能方面的分数与运动耐量、呼吸困难及日常活动相关,而心理方面的分数与焦虑和抑郁密切相关。
Anxiety scores accounted for 51 and 56% of the total explained variance in total CRQ and SRI scores, respectively. The emphasis of the MRF-28 was restrictions in activities of daily living (52% of total variance).
焦虑得分分别解释了CRQ和SRI总评分中51 and 56%的解释方差。MRF-28强调日常生活中活动能力的限制(占总方差的52%)。
In conclusion, the present study showed that the Maugeri Respiratory Failure and Severe Respiratory Insufficiency questionnaires were reliable and valid questionnaires in chronic obstructive pulmonary disease patients with chronic hypercapnic respiratory failure.
结论:目前研究表明,Mauger呼吸衰竭和严重呼吸功能不全问卷在评价伴有慢性高碳酸血症型呼衰的慢性阻塞性肺疾病患者上是有效可靠的。
While the emphasis in the Maugeri Respiratory Failure questionnaire is on activities of daily living, the Severe Respiratory Insufficiency questionnaire, like the Chronic Respiratory Questionnaire, is more related to anxiety and depression.
Maugeri呼吸衰竭问卷的重点是日常活动能力,而像慢性呼吸系统问卷一样,严重呼吸功能不全问卷更关注的是焦虑和抑郁。
Eur Respir J 2008; 32:379-386 COPD慢性呼衰患者健康相关的生活质量

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作者:admin@医学,生命科学    2011-04-30 17:14
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