NEW YORK (Reuters Health) Jul 22 - Between 2001-2006, 53% of the tuberculosis cases that occurred among foreign-born individuals in the US involved persons from sub-Saharan Africa or Southeast Asia, new research indicates.
"The relative yield of finding and treating latent TB infection is particularly high among individuals from most countries of sub-Saharan Africa and Southeast Asia," Dr. Kevin P. Cain and co-investigators, from the Centers for Disease Control and Prevention in Atlanta, state.
In 2006, the authors note, 57% of TB cases in the US involved foreign-born individuals. Present strategies to control TB have not adequately addressed the high frequency of disease and latent infection in this group, they add.
According to the new report, published in the Journal of the American Medical Association for July 23/30, 46,970 cases of TB disease were seen among foreign-born persons in the US during the study period. In 28% of these cases, the individuals had been in the US for 2 years or less.
As time since US entry increased, TB case rates fell among foreign-born persons. Nonetheless, even with 20 years since arrival, rates were higher among foreign-born than among US-born individuals.
The cases involving individuals from sub-Saharan Africa or Southeast Asia represented 22% of the foreign-born population from these regions.
Resistance rates of up to 20% and 18% were noted among recent entrants from Vietnam and Peru, respectively, the authors note.
Annually, 250 persons, on average, were diagnosed with smear-negative, culture-positive TB disease within 3 months of US entry, the report indicates. Of these cases, 46% involved individuals from the Philippines or Vietnam.
"Latent TB infection testing and treatment among foreign-born persons needs to be more widely implemented, but even when it cannot be fully implemented, its yield can be higher by focusing on the highest-risk populations of foreign-born persons first," the researchers emphasize.
JAMA 2008;300:405-412. [标签:content1][标签:content2]
作者:admin@医学,生命科学 2011-08-29 17:14