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【社会人文】飞机让给年轻人
Jet Setting Is For the Young
By Michael Balter
ScienceNOW Daily News
6 November 2006
As most jet setters know, life in the fast lane exacts a high price. Any departure from usual day/night routine can play havoc with biological clocks and lead to chronic jetlag. Now, a new study in mice suggests that jetlag--and analogous conditions suffered by shift workers and others--might be more than just a nuisance but a serious danger to health.
There have been surprisingly few studies of the dangers of chronic jetlag to humans. What little is known suggests the condition can increase the risk of cancer, peptic ulcers, and sleep disorders. These findings are of great concern to specialists in occupational medicine, because a growing number of shift workers--up to 75% according to a recent European Union study--are working shifts outside of the normal 8 AM to 5 PM work day. Moreover, the risk of illness from jetlag appears to be greater with advancing age.
To investigate the role of aging in jetlag, biologist Gene Block of the University of Virginia at Charlottesville and his colleagues exposed both young mice (8-12 months) and old mice (27-31 months) to light-cycle shifts over 8 weeks. One group made up of 9 young and 30 old mice had their day/night cycle moved forward 6 hours every week, while another group of similarly aged mice had its day/night cycle shifted 6 hours backwards every week. A control group was exposed to a normal cycle of 12 hours of light and 12 hours of darkness. While only 17% of the old control mice died during the study period, 53% of the old mice whose cycles were moved forward died and 32% of the old mice whose cycles were moved backward died. Only one young mouse died during the experiment.
The study sounds an important warning about the possible dangers of jetlag, especially among older people, the team concludes in tomorrow's issue of Current Biology. Francis Lévi, a researcher who studies cancer risk and biological rhythms at the Paul Brousse Hospital in Villejuif, France, says that the new study is consistent with several epidemiological studies in humans. "There is an increased risk of breast or colorectal cancer in women exposed to chronic shift work for longer than 15 years," Lévi says, adding that more research on the role of jet lag in illness should be a high priority.
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Jetlag facts ? 题目比较奇怪.
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As most jet setters know, life in the fast lane exacts a high price. Any departure from usual day/night routine can play havoc with biological clocks and lead to chronic jetlag. Now, a new study in mice suggests that jetlag--and analogous conditions suffered by shift workers and others--might be more than just a nuisance but a serious danger to health.
大部分乘飞机到处旅游的人知道，这种高速要付出很大代价。脱离正常日夜规律，可以对生物钟造成很大破坏，并可导致慢性时差综合征。最新小鼠实验表明，时差综合征以及困扰倒班人群的类似情况可能不仅仅是小麻烦，而是对健康的严重威胁。
There have been surprisingly few studies of the dangers of chronic jetlag to humans. What little is known suggests the condition can increase the risk of cancer, peptic ulcers, and sleep disorders. These findings are of great concern to specialists in occupational medicine, because a growing number of shift workers--up to 75% according to a recent European Union study--are working shifts outside of the normal 8 AM to 5 PM work day. Moreover, the risk of illness from jetlag appears to be greater with advancing age.
极少有研究关注慢性时差综合征对人体究竟有多大危害。人们仅仅知道，这种情况可以增加癌症、消化性溃疡及睡眠紊乱的发生风险。职业医学专家对此很担心，因为最近欧洲联合研究表明，高达75%的人工作时间 在正常的早上8点至下午5点以外，而且因时差综合征引起疾病的风险随年龄增长而增加。
To investigate the role of aging in jetlag, biologist Gene Block of the University of Virginia at Charlottesville and his colleagues exposed both young mice (8-12 months) and old mice (27-31 months) to light-cycle shifts over 8 weeks. One group made up of 9 young and 30 old mice had their day/night cycle moved forward 6 hours every week, while another group of similarly aged mice had its day/night cycle shifted 6 hours backwards every week. A control group was exposed to a normal cycle of 12 hours of light and 12 hours of darkness. While only 17% of the old control mice died during the study period, 53% of the old mice whose cycles were moved forward died and 32% of the old mice whose cycles were moved backward died. Only one young mouse died during the experiment.
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作者:admin@医学,生命科学 2011-06-11 17:27
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