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【medical-news】男性睡眠过多或过少都明显增加2
Men who sleep too much or too little are at an increased risk of developing Type 2 diabetes, according to a study by the New England Research Institutes in collaboration with Yale School of Medicine researchers.
The data published in the March issue of Diabetes Care were obtained from 1,709 men, 40 to 70 years old. The men were enrolled in the Massachusetts Male Aging Study and were followed for 15 years with home visits, a health questionnaire and blood samples.
Six to eight hours of sleep was found to be most healthy. In contrast, men who reported they slept between five and six hours per night were twice as likely to develop diabetes and men who slept more than eight hours per night were three times as likely to develop diabetes, according to the lead author, H. Klar Yaggi, M.D., professor in Yale's Department of Internal Medicine, pulmonary section. Previous data from the Nurses Health Study have shown similar results in women.
"These elevated risks remained after adjustment for age, hypertension, smoking status, self-rated health status and education," Yaggi said.
He said researchers are just beginning to recognize the hormonal and metabolic implications of too little sleep. Among the documented effects, Yaggi said, are striking alterations in metabolic and endocrine function including decreased carbohydrate tolerance, insulin resistance, and lower levels of the hormone leptin leading to obesity. The mechanisms by which long sleep duration increase diabetes risk requires further investigation.
"There is a lot of interest in determining whether sleep disturbances such as a reduced amount of sleep or disorders like sleep apnea may actually worsen the metabolic syndrome," said Yaggi. Metabolic syndrome is a cluster of risk factors including high blood pressure, obesity, high cholesterol and insulin resistance which increase the risk for heart disease and stroke.
http://www.yale.edu 男性睡眠过多或过少都明显增加2-型糖尿病患病机率
据新英格兰研究所和耶鲁医学院联合报道，男性睡眠过多或过少都明显增加2型糖尿病患病机率。
上述报道发表在《糖尿病护理》3月刊，相关数据显示该研究选取1709名40至70岁男性为研究对象，研究对象在麻萨诸塞州男性老化研究注册，以家访、健康问卷调查和抽血样的方式随访15年。
根据第一作者耶鲁大学内科呼吸组教授H. Klar Yaggi研究结果显示有益于健康的睡眠时间为6至8个小时。相反，每晚睡眠时间在5至6个小时的男性其糖尿病的发病率比正常睡眠时间的男性高出一倍，而每晚睡眠时间多于8小时的男性则比正常高出2倍。《护士健康研究》曾报道的女性睡眠和糖尿病的关系与男性有着相似的结果。
Yaggi说，在对年龄、高血压、吸烟和自身健康状态进行校正后，以上糖尿病升高的趋势仍然存在，我们正在寻找睡眠过少所带来的激素或代谢水平的改变，结果发现这些改变包括糖耐量的降低、胰导素抵抗和血清瘦素水平的降低以致肥胖。睡眠过多导致糖尿病发病率增高的机制尚需进一步研究。
Yaggi说，目前研究的热点聚焦于明确睡眠障碍如睡眠减少或呼吸暂停综合征是否会加重代谢综合征。代谢综合征是多种危险因素的总称，这些危险因素包括高血压、肥胖、高胆固醇血症和胰导素抵抗。代谢综合征可增加心脏疾病和中风的发生率。 已经是3月份的糖尿病护理了吧，我发过了 [标签:content1][标签:content2]
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作者:admin@医学,生命科学 2011-02-24 05:11
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