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【文摘发布】异种移植现状和未来展望

Title: Xenotransplantation: current status and a perspective on the future.

Author:Yang YG, Sykes M.

source:Nat Rev Immunol. 2007 Jun 15

IF:30.458(2005)

Xenotransplantation using pigs as the transplant source has the potential to resolve the severe shortage of human organ donors. Although the development of relatively non-toxic immunosuppressive or tolerance-inducing regimens will be required to justify clinical trials using pig organs, recent advances in our understanding of the biology of xenograft rejection and zoonotic infections, and the generation of alpha1,3-galactosyltransferase-deficient pigs have moved this approach closer to clinical application. This Review highlights the major obstacles impeding the translation of xenotransplantation into clinical therapies and the potential solutions, providing a perspective on the future of clinical xenotransplantation. 本人已认领该文编译,48小时后若未提交译文,请其他战友自由认领 .
Xenotransplantation: current status and a perspective on the future.
异种移植的现状和展望 个人观点,仅供参考:

Xenotransplantation using pigs as the transplant source has the potential to resolve the severe shortage of human organ donors.
猪作为最具潜力的异种供器官源可以解决人类供器官严重短缺的问题。
用猪作为异种移植器官来源有可能会解决人类供器官严重短缺的问题。 感谢假老师的指点,继续学习。

zoonotic infections译为“猪源人畜共患病”很贴切 谢谢! 行家一出手,就只有没有! 还是“假”行家啊!那真行家来了可怎么办? 能请各位探讨一下异种移植中猪的逆转录病毒的研究近况吗? 能提供全文下载吗,想好好读一遍 fulltext

the future Article Nature Reviews Immunology.htm (270.53k) [标签:content1][标签:content2]

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作者:admin@医学,生命科学    2011-02-23 05:11
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