主页 > 医药生命 >
【medical-news】针灸镇痛机理——Nautre Neuroscience
Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture
Acupuncture is an invasive procedure commonly used to relieve pain. Acupuncture is practiced worldwide, despite difficulties in reconciling its principles with evidence-based medicine. We found that adenosine, a neuromodulator with anti-nociceptive properties, was released during acupuncture in mice and that its anti-nociceptive actions required adenosine A1 receptor expression. Direct injection of an adenosine A1 receptor agonist replicated the analgesic effect of acupuncture. Inhibition of enzymes involved in adenosine degradation potentiated the acupuncture-elicited increase in adenosine, as well as its anti-nociceptive effect. These observations indicate that adenosine mediates the effects of acupuncture and that interfering with adenosine metabolism may prolong the clinical benefit of acupuncture.
全文地址
http://www.nature.com/neuro/journal/vaop/ncurrent/full/nn.2562.html
这是科学杂志对其的新闻报道
http://news.sciencemag.org/sciencenow/2010/05/how-acupuncture-pierces-chronic-.html?rss=1
注意了,第一作者Nanna Goldman是通讯作者16岁的女儿。。。 Adenosine A1 receptors mediate local anti-nociceptive effects of acupuncture
腺苷A1受体介导针灸的局部阵痛效果
Acupuncture is an invasive procedure commonly used to relieve pain.
针灸是一种广泛用于缓解疼痛的侵入式方法。 Acupuncture is practiced worldwide, despite difficulties in reconciling its principles with evidence-based medicine.尽管与循证医学的原则不同,针灸在世界上被广泛应用。 We found that adenosine, a neuromodulator with anti-nociceptive properties, was released during acupuncture in mice and that its anti-nociceptive actions required adenosine A1 receptor expression.我们发现腺苷,作为一种具有镇痛作用神经调质,在针灸的时候被释放出来,而且它的镇痛作用需要腺苷A1受体的表达。 Direct injection of an adenosine A1 receptor agonist replicated the analgesic effect of acupuncture.直接注射腺苷A1受体拮抗剂能够复制针灸的镇痛效果。 Inhibition of enzymes involved in adenosine degradation potentiated the acupuncture-elicited increase in adenosine, as well as its anti-nociceptive effect.抑制腺苷降解相关酶,能够增强针灸所引起的腺苷表达上调,并增强其镇痛作用。 These observations indicate that adenosine mediates the effects of acupuncture and that interfering with adenosine metabolism may prolong the clinical benefit of acupuncture.这些观察结果提示腺苷介导了针灸的镇痛作用,通过对腺苷代谢的干预,可以延长针灸的临床镇痛效果。 腺苷A1受体介导针灸的局部阵痛效果
针灸是一种广泛用于缓解疼痛的侵入式方法。尽管与循证医学的原则不同,针灸在世界上仍被广泛应用。我们发现作为一种具有镇痛作用神经调质,腺苷在针灸的时候被释放出来,而且其镇痛作用需要腺苷A1受体的表达。直接注射腺苷A1受体拮抗剂能够复制针灸的镇痛效果。抑制腺苷降解相关酶,能够增强针灸所引起的腺苷表达上调,并增强其镇痛作用。这些观察结果提示腺苷介导了针灸的镇痛作用,通过对腺苷代谢的干预,可以延长针灸的临床镇痛效果。 针灸用了这么多年,
研究了这么多年,
居然被一个老外,
一个16岁小姑娘发了neuroscience。。。
发人深思啊! 国内还有些人要叫嚣者要废除中医呢!!!尤其那个姓方的!!!!难道四大发明的教训还不够深吗???都是中国人的发明,结果却让老外发扬了广大!!!!
就像围棋………………现在的第一却是个韩国人。汗!!!! 国人的东西不能丢呀 个人认为,一味继续研究中医理论本身没有意义,这个理论本来就是个哲学,不是科学
但其中真正有实用意义我们却开发不出来 值得深思! 【medical-news】针灸镇痛机理——Nautre Neuroscience - 医药...发表时间:2010-5-31回帖数:6针灸镇痛机理,争论了好多年了,但我想这是第一个高水平杂志的正面报道吧 adenosine a... 针灸用了这么多年, 研究了这么多年, 居然被一个老外, 一个16岁小姑娘发了neuroscience...www.ruanjian520.com/thread-... - 2010-06-19-快照-【medical-news】针灸镇痛机理——Nautre Neuroscience - 医药..."[标签:content2]
阅读本文的人还阅读:
作者:admin@医学,生命科学 2011-01-12 23:25
医学,生命科学网