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【medical-news】癌症与糖尿病——令人生畏的组合
Reuters Health
Wednesday, May 2, 2007
NEW YORK (Reuters Health) - People with cancer who also have diabetes are often treated less aggressively and have a worse overall outlook than those without diabetes, Dutch investigators report.
Dr. Lonneke V. van de Poll-Franse, of the Comprehensive Cancer Center, Eindhoven, and colleagues examined the prevalence of diabetes among people recently diagnosed with cancer, along with the influence of diabetes on cancer stage at diagnosis, treatment and overall survival.
The subjects included 58,498 patients diagnosed between 1995 and 2002 and entered in a cancer registry. Patients were followed until January 1, 2005.
Nine percent of all cancer patients had diabetes at diagnosis, the investigators report in the International Journal of Cancer.
Patients with diabetes were more often diagnosed with advanced tumors than non-diabetic individuals. In addition, diabetics were treated with less chemotherapy and radiation than those without diabetes.
Overall, 3902 of 5555 cancer patients with diabetes and 29,909 of 52,943 cancer patients without diabetes died during follow-up.
After taking account of cancer stage at diagnosis, age, gender, and treatment, "we found that patients with diabetes experienced a significant increase in overall mortality," the investigators report. The increase ranged up to 40 percent, depending on the type of cancer.
"With the ageing of the population, the number of persons who suffer from more than one chronic disease is increasing," the researchers point out. "As a consequence, more and more patients require a multidisciplinary approach for their multiple diseases."
SOURCE: International Journal of Cancer, May 2007.
http://www.nlm.nih.gov/medlineplus/news/fullstory_48693.html 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领 Cancer and diabetes a daunting combination
癌症与糖尿病——令人生畏的组合
Reuters Health 路透社健康
Wednesday, May 2, 2007 2007-05-02 星期三
NEW YORK (Reuters Health) - People with cancer who also have diabetes are often treated less aggressively and have a worse overall outlook than those without diabetes, Dutch investigators report.
纽约（路透社健康）-与那些不患有糖尿病的癌症患者相比，患有糖尿病的癌症患者通常得到治疗力度较弱的治疗，并且整个疾病前景更糟糕，荷兰研究员们报道。
Dr. Lonneke V. van de Poll-Franse, of the Comprehensive Cancer Center, Eindhoven, and colleagues examined the prevalence of diabetes among people recently diagnosed with cancer, along with the influence of diabetes on cancer stage at diagnosis, treatment and overall survival.
综合肿瘤中心的Lonneke V. van de Poll-Franse Eindhoven博士和他的同事们调查了最近诊断为癌症的群体中糖尿病的患病率连同糖尿病在癌症发展中诊断、治疗和总生存数的影响。
The subjects included 58,498 patients diagnosed between 1995 and 2002 and entered in a cancer registry. Patients were followed until January 1, 2005.
受试者包括了在1995年到2002年中确诊的58,498名患者，并且输入进癌症登记处。这些患者进行了随访直到2005年1月1号。
Nine percent of all cancer patients had diabetes at diagnosis, the investigators report in the International Journal of Cancer.
所有癌症患者中有百分之九在诊断上患有糖尿病, 研究员们在《国际癌症杂志》上报告。
Patients with diabetes were more often diagnosed with advanced tumors than non-diabetic individuals. In addition, diabetics were treated with less chemotherapy and radiation than those without diabetes.
与非糖尿病个体相比，糖尿病患者常常在肿瘤早期就被确诊。另外, 糖尿病患者比非糖尿病者较少接受化疗和辐射治疗。
Overall, 3902 of 5555 cancer patients with diabetes and 29,909 of 52,943 cancer patients without diabetes died during follow-up.
总之,在随访期间，5555位糖尿病癌症患者中有3902位死亡，52,943 位非糖尿病癌症患者有29,909位死亡。
After taking account of cancer stage at diagnosis, age, gender, and treatment, "we found that patients with diabetes experienced a significant increase in overall mortality," the investigators report. The increase ranged up to 40 percent, depending on the type of cancer.
考虑到癌症在诊断、年龄、性别和治疗上的进展, “我们发现糖尿病癌症患者在总死亡率上有明显的增长”研究员们报告。根据癌症类型，增长（率）上涨到40%。
"With the ageing of the population, the number of persons who suffer from more than one chronic disease is increasing," the researchers point out. "As a consequence, more and more patients require a multidisciplinary approach for their multiple diseases."
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作者:admin@医学,生命科学 2010-10-11 05:11
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