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【medical-news】八旬老人经皮冠状动脉介入治疗（
By Martha Kerr
NEW YORK (Reuters Health) Dec 18 - Elective percutaneous coronary intervention (PCI) in patients who are in their eighties has an "acceptable outcome" in the stent era, with "acceptable short-term mortality." However, emergency PCI in this age group still carries substantial risk, New York investigators report in the current issue of the American Journal of Cardiology.
At New York Presbyterian Hospital-Weill Cornell Medical Center in New York City, Dr. Dmitriy N. Feldman and colleagues used the New York State Angioplasty Registry of 2000-2001 to compare in-hospital mortality and major adverse events (death, stroke or coronary artery bypass grafting) in three age groups: patients younger than 60 years of age, patients between 60 and 80 and patients older than 80 years of age.
There were 10,964 patients undergoing emergency PCI and 71,176 patients undergoing elective PCI.
Elderly patients were, in general, more unstable upon presentation and had more co-morbidities, including extensive coronary artery disease and other cardiovascular diseases.
For patients undergoing emergency PCI, the in-hospital mortality rates were 1.0%, 4.1% and 11.5% for patients in the youngest, middle and oldest age groups, respectively. Among patients undergoing elective PCI, mortality rates were 0.1%, 0.4% and 1.1%, respectively.
"Therefore, in the very elderly patients, a thorough discussion about risks and benefits of percutaneous revascularization is needed, particularly if emergency PCI is being considered, Dr. Feldman commented in correspondence with Reuters Health. However, a surgical revascularization option in this age group may carry an even higher rate of postprocedural complications compared with PCI."
"Our overall mortality in the 60-80 group was 0.8% and in the older than 80 group it was 2.2%, which is lower than previously reported in patients undergoing PCI in late 1990's. This suggests that PCI outcomes have improved in the era of widespread use of stenting and greater use of glycoprotein IIb/IIIa inhibitors," he pointed out.
Dr. Feldman concluded that "elective PCI procedures in the elderly are safe and have an acceptable short-term mortality when performed at experienced institutions." However, elderly patients undergoing emergency PCI continue to have a substantially higher risk of adverse events.
http://www.medscape.com/viewarticle/549519 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 【medical-news】八旬老人经皮冠状动脉介入治疗（PCI）的安全与风险
PCI in Octogenarians Becoming Safer but Risk Still Substantial
By Martha Kerr
NEW YORK (Reuters Health) Dec 18 - Elective percutaneous coronary intervention (PCI) in patients who are in their eighties has an "acceptable outcome" in the stent era, with "acceptable short-term mortality." However, emergency PCI in this age group still carries substantial risk, New York investigators report in the current issue of the American Journal of Cardiology.
纽约路透社健康报12月18号刊--对八旬老人上支架期间进行选择性经皮冠状动脉介入治疗（PCI）疗效尚可，有着“可接受的短期死亡率”。然而，这个年龄的急诊的PCI治疗仍有着潜在的危险，纽约调查者在美国心血管杂志的文章中进行了报道。
At New York Presbyterian Hospital-Weill Cornell Medical Center in New York City, Dr. Dmitriy N. Feldman and colleagues used the New York State Angioplasty Registry of 2000-2001 to compare in-hospital mortality and major adverse events (death, stroke or coronary artery bypass grafting) in three age groups: patients younger than 60 years of age, patients between 60 and 80 and patients older than 80 years of age.
在纽约Presbyterian Hospital-Weill Cornel医疗中心，Dr. Dmitriy N. Feldman和他的同事用纽约州2000-2001年度的血管成行术记录就三组年龄的住院病死率和主要不良事件进行了比较（死亡，休克和冠脉搭桥术）：《60岁，60-80岁，和》80岁三组。
There were 10,964 patients undergoing emergency PCI and 71,176 patients undergoing elective PCI.
有10964位患者进行了急诊PCI术，1176位患者进行了选择性PCI术。
Elderly patients were, in general, more unstable upon presentation and had more co-morbidities, including extensive coronary artery disease and other cardiovascular diseases.
一般来说，年龄相对较大的患者进行手术时情况更加不稳定，且有着更多的并发症，包括广泛的冠状动脉疾病和其他心血管疾病。
For patients undergoing emergency PCI, the in-hospital mortality rates were 1.0%, 4.1% and 11.5% for patients in the youngest, middle and oldest age groups, respectively. Among patients undergoing elective PCI, mortality rates were 0.1%, 0.4% and 1.1%, respectively.
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作者:admin@医学,生命科学 2011-03-14 05:11
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