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【medical-news】Euro评分将作为住院患者经皮介入治
Heart 2009;95:43-48
Objective: To date, no common risk stratification system is available to predict the risk of surgical or percutaneous myocardial revascularisation in patients with coronary artery disease (CAD). Thus, we sought to assess the European System for Cardiac Operative Risk Evaluation (EuroSCORE) validity to predict in-hospital mortality after percutaneous coronary intervention (PCI).
Design, setting and participants: EuroSCORE was prospectively and systematically assessed in 1173 consecutive patients undergoing PCI in a high-volume single centre between April 2005 and October 2006.
Main outcome measure: The receiver-operating characteristics (ROC) curve was used to describe performance and accuracy of the EuroSCORE risk model for the prediction of in-hospital mortality after PCI.
Results: The EuroSCORE model demonstrated an overall relation between EuroSCORE rank and the incidence of in-hospital mortality, showing consistency in predicting patient risk across many subgroups and levels of global risk. At multivariable logistic regression analysis the EuroSCORE value was an independent in-hospital mortality predictor (p = 0.002) together with left main disease (p = 0.005), procedural urgency (p = 0.001), ACC/AHA C type lesion (p = 0.02) and PCI failure (p = 0.01). The area under the ROC curve for the EuroSCORE system was 0.91 (95% CI 0.86 to 0.97), indicating a good ability of the model to discriminate patients at risk of dying during the index hospitalisation.
Conclusion: The EuroSCORE risk model, already extensively validated for the prediction of early mortality following open-heart surgery, can also be efficiently utilised in the setting of PCI. The introduction of the EuroSCORE assessment in patients with documented CAD may help to improve the revascularisation strategy decision-making process.
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In the last decade cardiac surgeons have successfully developed and validated several risk models for the prediction of early postoperative mortality, particularly for the comparison of results from different institutions and countries. In particular, in 1995 the European System for Cardiac Operative Risk Evaluation (EuroSCORE) risk model was conceived to predict in-hospital mortality for patients undergoing open-heart surgery.1 Owing to its simplicity and objectivity, this model has been subsequently validated in different subsets of patients and in different population studies.2–6 This scoring method is composed of groups of weighted patient-related, cardiac-related and procedural-related risk factors and it is available online at the EuroSCORE web page (www.euroscore.org). Indeed, this is the most updated surgical risk model and has the best discriminatory capacity among the existing risk score algorithms.7
More recently, several small-sized studies suggested that EuroSCORE could also be used for baseline percutaneous coronary intervention (PCI) risk stratification in selected high-risk procedures such as left main coronary artery stenting.8–10 Yet, a broader validation of the EuroSCORE to predict outcome in unselected patients with coronary artery disease (CAD) undergoing PCI, similar to that obtained for coronary surgery, may provide an immediate, better stratification of individual revascularisation-related risks.
In this prospective study we analysed the predictive power of the EuroSCORE risk model in the prediction of peri-procedural mortality in 1173 consecutive patients undergoing PCI. 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 EuroSCORE as predictor of in-hospital mortality after percutaneous coronary intervention
Heart 2009;95:43-48
EuroSCORE评分可作为经皮冠状动脉介入治疗（PCI）术后住院死亡率的预测因素。Heart 2009;95:43-48
Objective: To date, no common risk stratification system is available to predict the risk of surgical or percutaneous myocardial revascularisation in patients with coronary artery disease (CAD). Thus, we sought to assess the European System for Cardiac Operative Risk Evaluation (EuroSCORE) validity to predict in-hospital mortality after percutaneous coronary intervention (PCI).
目的：到目前为止，还没有通用的危险分层系统预测冠心病（ CAD ）患者手术或PCI的风险。因此，我们设法评估欧洲心脏手术风险评估系统（ EuroSCORE ）的有效性来预测PCI住院死亡。
Design, setting and participants: EuroSCORE was prospectively and systematically assessed in 1173 consecutive patients undergoing PCI in a high-volume single centre between April 2005 and October 2006.
设计，制定和参与者：2005年4月至2006年10月，在的单一大中心的1173连续PCI患者中用EuroSCORE进行前瞻性和系统性评估。
Main outcome measure: The receiver-operating characteristics (ROC) curve was used to describe performance and accuracy of the EuroSCORE risk model for the prediction of in-hospital mortality after PCI.
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作者:admin@医学,生命科学 2011-03-13 05:11
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