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【商业翻译】锂可降低复发性抑郁症引起的自杀
本稿件为《医师报》约稿，署名统一为“丁香”，稿酬按照医师报标准发放。
Lithium cuts suicide risk in recurrent depression
NEW YORK (Reuters Health) - In people suffering from recurrent major depressive disorder, treatment with lithium reduces the risk that they'll commit or attempt suicide, according to a new study
Lithium is commonly used to treat bipolar disorder, or manic depression. Because the drug has shown significant anti-suicide effects in this setting, Dr. Ross J. Baldessarini, of McLean Hospital, Belmont, Massachusetts, and colleagues looked for evidence that it might also benefit patients with recurrent major depression.
As reported in the Journal of Clinical Psychiatry, the investigators identified eight studies that reported on suicides or suicide attempts during treatment with and without lithium in patients with recurrent depression. Their analysis involved a total of 329 subjects.
The overall rate of suicidal acts was 1.48 percent annually among those not given lithium compared with 0.17 percent per year among those treated with lithium -- an 88.5 percent reduction in risk.
"The findings reported here support the conclusion that lithium may represent a useful supplemental or alternative treatment for potentially suicidal patients with recurrent major depressive disorder, as has been found in patients with bipolar disorders," the authors conclude.
SOURCE: Journal of Clinical Psychiatry, March 2007. 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领 Lithium cuts suicide risk in recurrent depression
锂盐可降低复发性抑郁症引起的自杀风险
NEW YORK (Reuters Health) - In people suffering from recurrent major depressive disorder, treatment with lithium reduces the risk that they'll commit or attempt suicide, according to a new study
路透社健康新闻纽约报道，根据一项新的研究显示，使用锂盐来治疗那些患有复发性重型抑郁症的人，可以降低他们犯罪或自杀的风险。
Lithium is commonly used to treat bipolar disorder, or manic depression. Because the drug has shown significant anti-suicide effects in this setting, Dr. Ross J. Baldessarini, of McLean Hospital, Belmont, Massachusetts, and colleagues looked for evidence that it might also benefit patients with recurrent major depression.
锂盐通常被用来治疗双向障碍或狂躁抑郁症。因为这种药物在治疗这些疾病时显示出显著的抗自杀效果。马萨诸塞州贝尔蒙特McLean医院的Ross J. Baldessarini医生和他的同事找到证据证明锂盐可能也有益于复发性重型抑郁症患者。
As reported in the Journal of Clinical Psychiatry, the investigators identified eight studies that reported on suicides or suicide attempts during treatment with and without lithium in patients with recurrent depression. Their analysis involved a total of 329 subjects.
正如临床精神医学杂志报道的那样，调查人员确定了8个关于在复发性抑郁症患者治疗过程中，使用锂盐和不使用锂盐治疗的患者中自杀或自杀倾向的研究报告。他们总共分析了329个病例。
The overall rate of suicidal acts was 1.48 percent annually among those not given lithium compared with 0.17 percent per year among those treated with lithium -- an 88.5 percent reduction in risk.
在那些没有接受锂盐治疗的患者中，一年中有自杀行为的占1.48%，而接受锂盐治疗的患者一年中有自杀行为占0.17%。相比较而言，接受锂盐治疗的患者自杀的风险降低了88.5%。
"The findings reported here support the conclusion that lithium may represent a useful supplemental or alternative treatment for potentially suicidal patients with recurrent major depressive disorder, as has been found in patients with bipolar disorders," the authors conclude.
文章的作者断定：“这里报导的结果支持这样一个结论：正如在治疗两极躁狂抑郁症中发现的那样，锂盐在治疗那些有潜在自杀倾向的复发性重型抑郁症患者时，可以成为一个实用的可追加的或可供选择的治疗方法。”
SOURCE: Journal of Clinical Psychiatry, March 2007.
来源：临床精神医学杂志2007年3月刊
编译：
锂盐可降低复发性抑郁症引起的自杀风险
路透社健康新闻纽约报道，根据一项新的研究显示，使用锂盐来治疗那些患有复发性重型抑郁症的人，可以降低他们犯罪或自杀的风险。
锂盐通常被用来治疗双向障碍或狂躁抑郁症。因为这种药物在治疗这些疾病时显示出显著的抗自杀效果。马萨诸塞州贝尔蒙特McLean医院的Ross J. Baldessarini医生和他的同事找到证据证明锂盐可能也有益于复发性重型抑郁症患者。
正如临床精神医学杂志报道的那样，调查人员确定了8个关于在复发性抑郁症患者治疗过程中，使用锂盐和不使用锂盐治疗的患者中自杀或自杀倾向的研究报告。他们总共分析了329个病例。在那些没有接受锂盐治疗的患者中，一年中有自杀行为的占1.48%，而接受锂盐治疗的患者一年中有自杀行为占0.17%。相比较而言，接受锂盐治疗的患者自杀的风险降低了88.5%。
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作者:admin@医学,生命科学 2011-02-28 17:11
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