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【medical-news】哈拂大学关于老年痴呆研究最近新

Opposite Enzyme Effect on Wild-type and Mutant Tau Raises Concerns over Popular Alzheimer’s ModelA key to untangling abnormal structures believed to be responsible for the demise of neurons in neurodegenerative diseases may lie in the interaction between two proteins, tau and Pin1.

Pin1 has a diametrically opposite impact on tau levels and tauopathy phenotype depending on whether the tau is wild-type or the P301L mutant.

http://www.mphtimes.com/bbs/viewthread.php?tid=691&extra=page%3D1

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作者:admin@医学,生命科学    2010-10-24 05:11
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