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【科普】减肥可缓解抑郁患者负面情绪！
ScienceDaily (July 29, 2009) — Research to be presented at the Annual Meeting of the Society for the Study of Ingestive Behavior (SSI finds that after a 6-month behavioral weight loss program, depressed patients not only lost 8% of their initial weight but also reported significant improvements in their symptoms of depression, as well as reductions in triglycerides, which are a risk factor for heart disease and stroke. The results of this study highlight the need for further research into the effects of weight loss in individuals suffering from psychiatric disorders.
“This research is novel because clinically depressed individuals are not usually included in weight loss trials due to concerns that weight loss could worsen their depression,” said Dr. Lucy Faulconbridge, lead author of the study. “These concerns, however, are not based on empirical evidence, and the practice of excluding depressed individuals from clinical weight loss trials means that we are learning nothing about this high-risk population.” The latest findings suggest that depressed, obese individuals can indeed lose clinically significant amounts of weight, and that weight loss can actually reduce symptoms of depression.
Fifty-one depressed and non-depressed subjects were recruited into the study to follow a supervised weight loss program that included lifestyle modification and meal replacements. Both depressed and non-depressed subjects lost significant amounts of weight, with depressed individuals losing 8% of their initial body weight, compared with 11% loss by non-depressed individuals. After 6 months on the weight loss program, depressed subjects also showed significant improvement of their depressive symptoms, based on a questionnaire.
Additional significant improvements in glucose, insulin and high density lipoprotein (HDL) cholesterol were observed in both depressed and non-depressed subjects, and depressed individuals showed reduced levels of triglycerides in the blood, which have been linked to risk of heart disease and stroke. “Depression and obesity are independently associated with increased risk of heart disease and stroke, and so reductions in both body weight and symptoms of depression are likely to improve long-term health outcomes” said Faulconbridge.
This research was supported by NIDDKK069652-04 and National Institute of Health.
The lead author was Lucy Faulconbridge, University of Pennsylvania School of Medicine, Philadelphia, PA, USA. Co-authors were TA WADDEN, LS JONES-CORNEILLE, DB SARWER, M PULCINI, L BERGELSON. University of Pennsylvania School of Medicine, Philadelphia, PA, USA.
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Adapted from materials provided by Society for the Study of Ingestive Behavior.
http://www.sciencedaily.com/releases/2009/07/090727102028.htm 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 Weight Loss Improves Mood In Depressed People, New Research Shows
减肥可缓解抑郁患者负面情绪
原文链接： http://www.sciencedaily.com/releases/2009/07/090727102028.htm
ScienceDaily (July 29, 2009) — Research to be presented at the Annual Meeting of the Society for the Study of Ingestive Behavior finds that after a 6-month behavioral weight loss program, depressed patients not only lost 8% of their initial weight but also reported significant improvements in their symptoms of depression, as well as reductions in triglycerides, which are a risk factor for heart disease and stroke. The results of this study highlight the need for further research into the effects of weight loss in individuals suffering from psychiatric disorders.
每日科学（ 2009年7月29日） -在吸收相关行为学会的年度会议发表的研究表明：在施行6个月的减肥计划行为后，抑郁症患者不仅减去了8 ％的体重，而且还初步报告其抑郁症的症状显著改善，并减少了甘油三脂，这是一个心脏病和中风的危险因素。这项研究的结果显著表明需要进一步研究患有精神疾病的患者体重减轻对其的影响。
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“This research is novel because clinically depressed individuals are not usually included in weight loss trials due to concerns that weight loss could worsen their depression,” said Dr. Lucy Faulconbridge, lead author of the study. “These concerns, however, are not based on empirical evidence, and the practice of excluding depressed individuals from clinical weight loss trials means that we are learning nothing about this high-risk population.” The latest findings suggest that depressed, obese individuals can indeed lose clinically significant amounts of weight, and that weight loss can actually reduce symptoms of depression.
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作者:admin@医学,生命科学 2010-10-22 13:08
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