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【文摘发布】一种新型无技术依赖性的自主导航
Author:Vucelic B, Rex D, Pulanic R, Pfefer J, Hrstic I, Levin B, Halpern Z, Arber N.
Resource:Gastroenterology. 2006 Mar;130(3):672-7
Abstract: BACKGROUND & AIMS: Endoscopic screening of the colon with available instruments requires considerable training, is often painful, and carries a risk of perforation. New instrument platforms for endoscopic screening could be useful. The aim of this study was to evaluate the extent of colonic intubation by using a novel self-propelled, self-navigating endoscope (the Aer-O-Scope; GI View Ltd, Ramat Gan, Israel). METHODS: Twelve young healthy volunteers underwent complete bowel preparation followed by a nonsedated examination using the novel device. Each examination was followed by a standard colonoscopy for safety evaluation. Cecal intubation was confirmed by endoscopic landmarks and fluoroscopy. RESULTS: In 10 out of 12 subjects (83%) the cecum was successfully reached, whereas in 2 cases the Aer-O-Scope advanced to the hepatic flexure. The time to complete advancement to cecum averaged 14.0 +/- 7 minutes, and the driving pressures averaged 34 +/- 2.3 milibar. Two subjects requested analgesics during the procedures (in both cases the cecum was reached). Four subjects experienced sweating and a bloating sensation that resolved spontaneously. All subjects were followed up to 48 hours and then for 30 days postprocedure, and no complications were observed. CONCLUSIONS: In a preliminary pilot feasibility study of this new instrument, the Aer-O-Scope effectively intubated all or most of the colon. Further clinical studies are warranted.
PMID:16530508 本人认领此文。如在48小时内未能提交译文，其他战友可自由认领。 Title: The aer-o-scope: proof of concept of a pneumatic, skill-independent, self-propelling, self-navigating colonoscope.
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首次人体试验一种新型无技术依赖性的自主导航及自主推进的气囊结肠镜：Aer-o-scope
Author:Vucelic B, Rex D, Pulanic R, Pfefer J, Hrstic I, Levin B, Halpern Z, Arber N.
作者：Vucelic B, Rex D, Pulanic R, Pfefer J, Hrstic I, Levin B, Halpern Z, Arber N.
Resource:Gastroenterology. 2006 Mar;130(3):672-7
来源：医学杂志《Gastroenterology》，2006年3月；130卷第3期672-7页
Abstract: BACKGROUND & AIMS: Endoscopic screening of the colon with available instruments requires considerable training, is often painful, and carries a risk of perforation. New instrument platforms for endoscopic screening could be useful. The aim of this study was to evaluate the extent of colonic intubation by using a novel self-propelled, self-navigating endoscope (the Aer-O-Scope; GI View Ltd, Ramat Gan, Israel). METHODS: Twelve young healthy volunteers underwent complete bowel preparation followed by a nonsedated examination using the novel device. Each examination was followed by a standard colonoscopy for safety evaluation. Cecal intubation was confirmed by endoscopic landmarks and fluoroscopy. RESULTS: In 10 out of 12 subjects (83%) the cecum was successfully reached, whereas in 2 cases the Aer-O-Scope advanced to the hepatic flexure.The time to complete advancement to cecum averaged 14.0 +/- 7 minutes, and the driving pressures averaged 34 +/- 2.3 milibar. Two subjects requested analgesics during the procedures (in both cases the cecum was reached). Four subjects experienced sweating and a bloating sensation that resolved spontaneously. All subjects were followed up to 48 hours and then for 30 days postprocedure, and no complications were observed. CONCLUSIONS: In a preliminary pilot feasibility study of this new instrument, the Aer-O-Scope effectively intubated all or most of the colon. Further clinical studies are warranted.
概述：
背景与目的：以现有的仪器做结肠镜检查（医生）需要大量的培训，（病人）经常很痛苦，且伴有穿孔的危险。新设备平台下的内窥镜检查能够解决这些问题。这项研究的目的是应用一种新型自主推进、自主导航的内窥镜来评估结肠插管的安全有效性（the Aer-O-Scope；GI View 有限责任公司，Ramat Gan 以色列）。
方法：12名年轻健康的志愿者都经历了完整的肠道准备以及用新仪器无镇静检查。每次检查都伴随着一项标准结肠镜检查的安全评估，盲肠插管通过透视镜标记和荧光检查得到证实。
结果：在12个志愿者中有10个(83%)的盲肠成功到达，而在另外2个中Aer-O-Scope最远到达了结肠肝曲。完全到达盲肠的平均时间为14.0 +/- 7分，前进的平均压力为34 +/- 2.3毫巴。两个受试者在进行中要求止痛（在这两种情况下达成的盲肠），4个受试者潜意识有出汗和肿胀感。所有受试者观察48小时，且随访30天无并发症。
结论：通过对这项新的仪器的可行性研究，Aer-O-Scope插管的有效范围为结肠的全部或大部。值得进一步临床研究。
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作者:admin@医学,生命科学 2010-10-17 05:11
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