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【medical-news】戒烟就让你多活三年
"Smoking cessation turned out to have a greater effect on reducing the risk of mortality after CABG than any other intervention or treatment," say Ron van Domburg (Erasmus Medical Center, Rotterdam, The Netherlands) and colleagues.
The team identified 551 (53%) smokers among 1041 patients who underwent CABG between 1971 and 1980, at an average age of 51 years. Of the smokers, 43% quit after CABG and sustained this through the first year.
The 10-, 20-, and 30-year survival rates were 88%, 49%, and 19%, respectively, among smokers who quit; but the corresponding rates among persistent smokers were just 77%, 36%, and 11% (p<0.0001 for overall survival difference).
Cumulative survival was similar among persistent smokers and nonsmokers.
When comparing quitters with persistent smokers, quitting smoking was the most important survival factor, reducing patients' mortality risk by 40%. Other independent predictors of mortality were older age, impaired left ventricular fraction, and triple-vessel disease.
The protective effect of quitting smoking equated to an additional 3.5 years' life expectancy in patients younger than 50 years, 2.8 years in those aged 50-60 years, and 1.7 years in those older than 60 years.
The overall life expectancy was 20 years among patients who quit smoking versus 17 years in those who persisted, the researchers note in the American Heart Journal.
"Smoking cessation programs should start immediately, during hospitalization, after acute myocardial infarction, CABG, percutaneous coronary intervention, and vascular surgery to have the greatest probability of success," observes the team.
http://www.mphtimes.com/us/index.php?option=com_content&view=article&id=521:smoking-cessation-may-add-3-years-to-post-cabg-survival&catid=137:smoking--quit-smoking&Itemid=139 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 Coronary patients who smoke can potentially add 3 years to their life expectancy after coronary artery bypass grafting (CABP) by quitting the habit, research suggests.
研究表明冠心病患者行冠脉搭桥术（coronary artery bypass grafting ，CABP）术后戒烟可使寿命延长3年以上。
"Smoking cessation turned out to have a greater effect on reducing the risk of mortality after CABG than any other intervention or treatment," say Ron van Domburg (Erasmus Medical Center, Rotterdam, The Netherlands) and colleagues.
荷兰鹿特丹Erasmus医学中心的Ron van Domburg及其同事说，与其他任何干预措施或治疗相比，戒烟对降低CABG术后的死亡率贡献最大。
The team identified 551 (53%) smokers among 1041 patients who underwent CABG between 1971 and 1980, at an average age of 51 years. Of the smokers, 43% quit after CABG and sustained this through the first year.
该研究从1971年到1980年共纳入1041例行CABG的病人，平均年龄51岁。烟民共有551例（53%），其中43%的患者在术后立即或一年后戒烟。
The 10-, 20-, and 30-year survival rates were 88%, 49%, and 19%, respectively, among smokers who quit; but the corresponding rates among persistent smokers were just 77%, 36%, and 11% (p<0.0001 for overall survival difference).
戒烟患者的10年、20年、30年生存率分别为88%、49%、19%，而未戒烟患者的仅分别为77%、36%、11%（p<0.0001，总生存率差异明显）
Cumulative survival was similar among persistent smokers and nonsmokers.
未戒烟者与不吸烟者 摘译如下：
荷兰鹿特丹Erasmus医学中心的Ron van Domburg及其同事最近在美国心脏杂志上发表的研究，发现冠心病患者行冠脉搭桥术（coronary artery bypass grafting ，CABP）后戒烟可使寿命延长3年以上。
他们的研究从1971年到1980年共纳入1041例行CABG的病人，平均年龄51岁。烟民共有551例（53%），其中43%的患者在术后立即或一年后戒烟。研究发现戒烟患者的10年、20年、30年生存率分别为88%、49%、19%，而未戒烟患者的仅分别为77%、36%、11%（p<0.0001，总生存率差异明显），但未戒烟者与戒烟者的累积生存率相同。死亡率的独立预测因子有年龄较大、左心室射血功能下降和三支血管病变等，但戒烟对降低CABG术后的死亡率贡献最大，戒烟是最重要的生存因子，使病人的死亡率下降近40%。戒烟可为50岁以下患者、50-60岁患者、60岁以上患者分别带来3.5、2.8、1.7年的生存优势。戒烟者的总生存期为20年，而未戒烟者仅为17年。研究者称，戒烟运动在发生急性心肌梗死、行CABG、冠状动脉造影和血管手术后的住院期间就应该开始，以期带来最佳的生存受益。 Cumulative survival
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作者:admin@医学,生命科学 2010-10-09 17:11
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