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sciencedaily编译－适量饮酒加强新神经细胞成形
相对长时间的适量饮酒能加强成年人大脑新的神经细胞成形。这些新细胞证明酒精依赖性发展和其他由于酒精对大脑产生的长期效应的重要性。Karolinska（卡洛琳斯）研究所发布了这个实验结果。
小鼠实验研究检测的酒精消耗量与正常社会调查的一致。结果显示适量饮酒能加强成年人大脑新的神经细胞成形。细胞存活并发展成正常形态的神经细胞。然而，神经萎缩并不增加。
这些天来，新的神经细胞在成人大脑中逐渐成形的观念已被普遍接受。有一个假设认为这些新的神经元细胞可能对学习和记忆有重要作用。许多因素影响新细胞成形的数目，例如压力、抑郁、身体活动及抗抑郁药。
副教授Stefan Brené说：“我们认为在适量饮酒过程中新神经细胞加速增殖对饮酒成瘾性发展和其他由于酒精对大脑产生的长期效应有重要意义。”
“这可能是由于适量饮酒产生的安定效应导致新的脑细胞成形，抗抑郁药与之有很多相似性。”
随着这些惊人的发现，现在研究者们明白了这些新的神经细胞在大脑活动中发挥的作用。
http://www.sciencedaily.com/releases/2005/05/050508211456.htm
Source: Karolinska Institutet
Date: 2005-05-09
Moderate Alcohol Consumption Enhances The Formation Of New Nerve Cells
Moderate alcohol consumption over a relatively long period of time can enhance the formation of new nerve cells in the adult brain. The new cells could prove important in the development of alcohol dependency and other long-term effects of alcohol on the brain. The findings are published by Karolinska Institutet.
The study, which was carried out on mice, examined alcohol consumption corresponding to that found in normal social situations. The results show that moderate drinking enhances the formation of new cells in the adult brain. The cells survive and develop into nerve cells in the normal manner. No increase in neuronal atrophy, however, could be demonstrated.
It is generally accepted these days that new nerve cells are continually being formed in the adult brain. One suggestion is that these new neurons could be important for memory and learning. The number of new cells formed is governed by a number of factors such as stress, depression, physical activity and antidepressants.
“We believe that the increased production of new nerve cells during moderate alcohol consumption can be important for the development of alcohol addiction and other long-term effects of alcohol on the brain,” says associate professor Stefan Brené.
“It is also possible that it is the ataractic effect of moderate alcohol consumption that leads to the formation of new brain cells, much in the same way as with antidepressive drugs.”
The researchers are now following up these exciting findings to understand the role that the new nerve cells thus formed play in cerebral activity.
Publication:
Moderate ethanol consumption increases hippocampal cell proliferation and neurogenesis in the adult mouse
Aberg E, Hofstetter C, Olson L, Brené S.
Int J Neuropsychopharm Online May 21, 2005, see http://journals.cambridge.org [标签:content1][标签:content2]
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作者:admin@医学,生命科学 2011-03-28 17:11
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