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【medical-news】抑郁可能是帕金森氏症的早期征兆
Main Category: Parkinson's Disease News
Article Date: 29 Apr 2007 - 0:00 PDT
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DepressionNeurology / NeurosciencePublic Health
Depression may be an early symptom of Parkinson's disease, according to research that will be presented at the American Academy of Neurology's 59th Annual Meeting in Boston, April 28 May 5, 2007.
The study looked at whether people who are taking antidepressant medications are more likely to develop Parkinson's disease than people who are not taking the medications. It found that, in the year before their Parkinson's disease was diagnosed, people who were taking antidepressants were nearly twice as likely to develop Parkinson's disease as those who were not taking antidepressants.
"This should not be interpreted as evidence that antidepressants cause Parkinson's disease," said Miguel Hernan, MD, DrPH, of Harvard School of Public Health in Boston. "The relationship is only apparent in the year before the onset of the disease, which suggests that depression is an early symptom of the disease."
For the study, researchers examined a database of more than three million people in the United Kingdom and identified 1,052 people with Parkinson's disease and matched them with 6,634 people without the disease. Then they looked at antidepressant use before the onset of Parkinson's disease.
The increased risk of developing Parkinson's in the year before diagnosis was true for both men and women, across age groups, and for those who used both types of antidepressants, tricyclic antidepressants and SSRIs, or selective serotonin reuptake inhibitors.
The American Academy of Neurology, an association of over 20,000 neurologists and neuroscience professionals, is dedicated to improving patient care through education and research. A neurologist is a doctor with specialized training in diagnosing, treating and managing disorders of the brain and nervous system such as Alzheimer's disease, epilepsy, multiple sclerosis, Parkinson's disease, and stroke.
http://www.medicalnewstoday.com/medicalnews.php?newsid=69260 译文
Depression May Be Early Sign Of Parkinson's Disease
Main Category: Parkinson's Disease News
Article Date: 29 Apr 2007 - 0:00 PDT
| email this article | printer friendly | view or write opinions | Article Also Appears In
DepressionNeurology / NeurosciencePublic Health
抑郁可能是帕金森氏症的早期征兆
分类：帕金森氏症新闻
文章日期：2007.04.29 美国太平洋时区0：00
文章还出版于抑郁神经病学与神经科学公共健康杂志上
Depression may be an early symptom of Parkinson's disease, according to research that will be presented at the American Academy of Neurology's 59th Annual Meeting in Boston, April 28 May 5, 2007.
将于2007年5月5日在波士顿举行的美国神经病学会第59届年会上公布的一项研究提示，抑郁可能是帕金森氏症的一个早期征兆。
The study looked at whether people who are taking antidepressant medications are more likely to develop Parkinson's disease than people who are not taking the medications. It found that, in the year before their Parkinson's disease was diagnosed, people who were taking antidepressants were nearly twice as likely to develop Parkinson's disease as those who were not taking antidepressants.
这项研究观察了服用抗抑郁药的患者是否较不服用抗抑郁药的患者更容易发展为帕金森氏症。研究结果发现，在被诊断为帕金森氏症的前一年，服用抗抑郁药患者最终发展为帕金森氏症的风险约是不服用抗抑郁药患者的2倍。
"This should not be interpreted as evidence that antidepressants cause Parkinson's disease," said Miguel Hernan, MD, DrPH, of Harvard School of Public Health in Boston. "The relationship is only apparent in the year before the onset of the disease, which suggests that depression is an early symptom of the disease."
“这个结果不应当被解读为抗抑郁药可引起帕金森氏症”波士顿哈佛大学公卫学院医学博士 Miguel Hernan认为“这种关系仅发生在帕金森氏症被诊断的前一年，提示抑郁可能是帕金森氏症的一个早期征兆”。
For the study, researchers examined a database of more than three million people in the United Kingdom and identified 1,052 people with Parkinson's disease and matched them with 6,634 people without the disease. Then they looked at antidepressant use before the onset of Parkinson's disease.
在这项研究中，研究者检查了英国3百多万名患者的资料，确定了其中1052名帕金森氏症患者，并对比研究了6634名非帕金森氏症患者，观察他们在帕金森氏症被诊断之前的抗抑郁药使用情况。
The increased risk of developing Parkinson's in the year before diagnosis was true for both men and women, across age groups, and for those who used both types of antidepressants, tricyclic antidepressants and SSRIs, or selective serotonin reuptake inhibitors.
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作者:admin@医学,生命科学 2011-03-24 21:16
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