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【drug-news】WHO: 明年需要全新流感疫苗
Whole new flu vaccine needed next year: WHO
WASHINGTON (Reuters) - The three most common influenza viruses circulating globally have changed significantly and next year's flu vaccines should be updated, the World Health Organization recommended.
A flu epidemic is well under way in the United States, and the U.S. Centers for Disease Control and Prevention said it had clear indications that the viruses have mutated, making the current vaccine less effective.
WHO said similar reports were coming in globally and it appears next year's vaccine will have to be completely new.
"Forty-four states reported widespread influenza activity," the CDC said in its weekly flu report on Friday. Ten American children have died of flu this season, the CDC said.
About one third of people tested for flu because of their symptoms actually had influenza, the CDC said. Other viruses cause similar symptoms to flu, marked by a sudden onset of fever, muscle aches and weakness.
Influenza viruses mutate constantly. Because of this, experts meet throughout the year to monitor the flu seasons and consider how to formulate the vaccine.
Flu vaccines contain the three most common circulating strains, usually two "A" strains and one "B" strain.
"As in previous years, national control authorities should approve the specific vaccine viruses used in each country," the WHO said.
Even if the flu vaccine is not a perfect match, it can protect people against the most serious effects of the infection. In an average year flu kills between 250,000 and 500,000 people globally.
Four antiviral drugs can help treat a case of the flu, but the WHO said H1N1 viruses in 18 countries had developed mutations that made them resist the effects of the best drug, Tamiflu, or oseltamivir, made by Roche AG and Gilead Sciences.
Resistance to the older drugs, amantadine and rimantadine, is now so widespread that their use is no longer recommended.
Companies usually begin the process of making new flu vaccines several months before the new flu season starts. Flu vaccines are made using a time-consuming process that involves chicken eggs.
WHO starts the process of helping advise companies -- and the governments that buy their vaccines -- on which three flu strains would best protect the most people in the upcoming flu season. (Reporting by Maggie Fox; Editing by Will Dunham) 明年需要全新的流感疫苗：WHO
WASHINGTON (Reuters) - The three most common influenza viruses circulating globally have changed significantly and next year's flu vaccines should be updated, the World Health Organization recommended.
华盛顿（路透社）- 席卷全球的三个最常见的流感病毒株已经显著变异，世界卫生组织建议更新明年的流感疫苗。
A flu epidemic is well under way in the United States, and the U.S. Centers for Disease Control and Prevention said it had clear indications that the viruses have mutated, making the current vaccine less effective.
在美国流感的传播正在进行，美国疾控预防中心声称，有清楚的证据表明这些病毒已经变异，当前的疫苗效力更低了。
WHO said similar reports were coming in globally and it appears next year's vaccine will have to be completely new.
世卫组织说全球范围都有类似的报告，看起来明年的疫苗必须完全更新了。
"Forty-four states reported widespread influenza activity," the CDC said in its weekly flu report on Friday. Ten American children have died of flu this season, the CDC said.
“44个州都发现广泛的流感活动特征，”疾控中心在周五的每周流感报告中声称。该季度已经有10个孩子死于流感。
About one third of people tested for flu because of their symptoms actually had influenza, the CDC said. Other viruses cause similar symptoms to flu, marked by a sudden onset of fever, muscle aches and weakness.
疾控中心说，因为病征接受流感检测的人有三分之一确证患流感。别的病毒会引起流感类似的症状，特征是突然的发烧，肌肉酸痛和衰弱。
Influenza viruses mutate constantly. Because of this, experts meet throughout the year to monitor the flu seasons and consider how to formulate the vaccine.
流感病毒一直在变异。因此一年来专家一直在监测病毒和研制疫苗。
Flu vaccines contain the three most common circulating strains, usually two "A" strains and one "B" strain.
流感疫苗含有三个常见的环状链，通常俩个A链和一个B链。
"As in previous years, national control authorities should approve the specific vaccine viruses used in each country," the WHO said.
“同以前一样，国家权力部门会批准在本国使用的特定疫苗，”WHO说。
Even if the flu vaccine is not a perfect match, it can protect people against the most serious effects of the infection. In an average year flu kills between 250,000 and 500,000 people globally.
即使该疫苗不是最好的，也可以帮人们抵御感染引起的症状恶化。全球平均每年流感致死的人数约25万到50万。
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作者:admin@医学,生命科学 2011-02-17 18:04
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