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【medical-news】月经可以作为干细胞的来源？也许
By ANDREW POLLACK
Published: January 29, 2008
In the past, menstruation was often viewed as a sign of uncleanliness or shame. In some cultures, women have been banished to huts or forbidden to cook during their periods.
So the prospect that “the curse” might be a source of stem cells to sustain life was a surprise to some experts.
“All the years I’ve been working in cell therapy, nobody ever thought of looking there,” said Dr. Stephen J. Noga, director of medical oncology and hematology at Sinai Hospital in Baltimore. Dr. Noga is also chairman of the scientific advisory board of Cryo-Cell International, the company marketing a menstrual blood collection and storage service.
Still, perhaps it should not be totally surprising. The endometrium, the lining of the uterus, regenerates each month, suggesting the presence of stem cells. Indeed, scientists have found such endometrial stem cells.
It is possible that the stem cells claimed to be in menstrual fluid are endometrial stem cells that slough off each month during menstruation.
But Caroline Gargett, a scientist at Monash University in Australia who has characterized endometrial stem cells, said it would be strange if lots of these valuable stem cells were shed in menstruation.
“If you lose them permanently, you won’t be able to grow the tissue,” she said.
Dr. Hugh Taylor, chief of reproductive endocrinology at Yale, said the healthiest stem cells would come from the part of the menstrual cycle when the uterine lining regenerates. “The menstrual fluid — those cells are dying,” he said.
Dr. Taylor also said a woman could always have cells taken directly from the endometrium by a uterine biopsy, which is routinely performed for fertility examinations. Even after menopause, he said, the uterine lining can be stimulated to grow by giving a woman estrogen.
“I think it’s premature to start telling anyone to go in and save their menses,” he said. “A woman can come in and have endometrial biopsy all the time and get those cells in a fresh, pure form.”
http://www.nytimes.com/2008/01/29/health/29bloo.html?ref=health 本人认领此文编译，若48h未上传译文，请其他战友自由认领 Menstruation as a Source of Stem Cells? Maybe Not
月经可作为干细胞的来源之一？或许不是
By ANDREW POLLACK
Published: January 29, 2008
In the past, menstruation was often viewed as a sign of uncleanliness or shame. In some cultures, women have been banished to huts or forbidden to cook during their periods.
在过去，月经被看着是不干净和羞耻的。在某些文化里，女性月经期间被驱除到茅舍居住或禁止煮饭。
So the prospect that “the curse” might be a source of stem cells to sustain life was a surprise to some experts.
所以一些专家对于“这个诅咒”可能是干细胞来源之一来维系着生命的观点表示奇怪。
“All the years I’ve been working in cell therapy, nobody ever thought of looking there,” said Dr. Stephen J. Noga, director of medical oncology and hematology at Sinai Hospital in Baltimore. Dr. Noga is also chairman of the scientific advisory board of Cryo-Cell International, the company marketing a menstrual blood collection and storage service.
Dr. Stephen J. Noga（Sinai医院，Baltimore，血液/肿瘤科主任）说：“我一直从事细胞治疗工作，但从没人想过从这里寻找突破口。”Dr. Noga还是Cryo-Cell国际公司顾问委员会主席，该公司从事月经血收集和储存业务。
Still, perhaps it should not be totally surprising. The endometrium, the lining of the uterus, regenerates each month, suggesting the presence of stem cells. Indeed, scientists have found such endometrial stem cells.
或许不应该如此惊讶。位于子宫的子宫内膜，每月更新一次，提示干细胞的存在。实际上，科学家们亦发现此类子宫内膜干细胞。
It is possible that the stem cells claimed to be in menstrual fluid are endometrial stem cells that slough off each month during menstruation.
在月经液中的干细胞可能就是每次月经时脱落的子宫内膜干细胞。
But Caroline Gargett, a scientist at Monash University in Australia who has characterized endometrial stem cells, said it would be strange if lots of these valuable stem cells were shed in menstruation.
但Caroline Gargett（Monash大学，澳大利亚，其发现子宫内膜干细胞）说：很多的这种有价值的干细胞脱落到月经液中应该令人感到惊讶。
“If you lose them permanently, you won’t be able to grow the tissue,” she said.
她说：“一旦丢失，将不能生长出新的组织。”
Dr. Hugh Taylor, chief of reproductive endocrinology at Yale, said the healthiest stem cells would come from the part of the menstrual cycle when the uterine lining regenerates. “The menstrual fluid — those cells are dying,” he said.
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作者:admin@医学,生命科学 2011-06-17 05:14
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