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【科普】严重的抑郁症与糖尿病的关系

24-APR-2007
Study Finds Major Depression Connection to Diabetes
严重的抑郁症与糖尿病的关系

WASHINGTON (Reuters) - Elderly people who are depressed are more likely to become diabetic than those who are not, according to a study that suggests depression may play a role in causing the most common form of diabetes.
华盛顿路透---患抑郁症的壮年人比无抑郁症的人更容易患糖尿病,根据一项研究指出,抑郁在糖尿病的发病中起最常见的作用
Writing on Monday in the Archives of Internal Medicine, the researchers said people with a high number of symptoms of depression were about 60 percent more likely to develop type 2 diabetes, formerly called adult-onset diabetes, than people who are not depressed.
国内医学文献周一的文章,研究人员称,抑郁症状显著的人比无抑郁症的人发生2型糖尿病的机率多60%
Unlike some other studies examining a link between depression and diabetes, this one looked at the effects not only of single bouts of depression but also of chronic depression and depression that worsened over time. It found an increased risk for diabetes in each of those scenarios.
与其他研究抑郁症和糖尿病关系的资料不同,本研究不仅是对短期抑郁发作,而且是慢性抑郁以及日益加重的抑郁 ,各种情节都会增加糖尿病的危险
Researchers tracked 4,681 men and women in North Carolina, California, Maryland and Pennsylvania ages 65 and older, with an average age of 73, who did not have diabetes when the study began in 1989.
研究人员对加利弗里亚,卡洛林啦。玛丽兰和宾夕凡尼亚各个州的65岁以上,平均年龄73的4,681个男性和女性进行追踪
For 10 years, they were screened annually for 10 symptoms of depression, including those related to mood, irritability, calorie intake, concentration and sleep.
10年,他们每年都检测抑郁症的症状,包括情绪,兴奋,热卡摄入量,精力集中和睡眠情况
"People who report higher depressive symptoms may not take as good a care of themselves as they should," lead researcher Mercedes Carnethon of the Northwestern University's Feinberg School of Medicine said in an interview.
研究人员主任Mercedes Carnethon在接受采访时说“抑郁症状越重,越不能很好的照顾自己”
"For example, they may be less physically active, and thus more likely to gain weight, which is the primary risk factor for diabetes," Carnethon said.
例如,他们的体力活动少,体重也高,这就是糖尿病主要危险因素“
But the study statistically accounted for known lifestyle risk factors for diabetes like being overweight and sedentary, and still found that depression increased the risk of diabetes.
不过,这项研究,对诸如超重和久坐,这些已知的生活方式的危险因素,进行了统计学计算,仍然发现,抑郁增加糖尿病的危险
Carnethon said the findings suggest depression may play a role in causing diabetes. While the study did not explore possible biological mechanisms, Carnethon said a high level of the stress hormone cortisol in depressed people may be the reason.
Mercedes Carnethon说,这些发现提示,尽管这项研究未能揭示可能存在的生物学机制,抑郁在糖尿病的原因中仍然起了主要作用,抑郁病人的压抑激素,可地松(肾上腺皮质激素)水平高,可能是一个原因
Diabetes is marked by high levels of blood glucose resulting from defects in the production or action of insulin, which allows glucose to enter the body's cells for use as fuel. High cortisol levels, the researchers said, may cut insulin sensitivity and raise fat deposits around the waist.
糖尿病人是由于胰岛素生产不足,或工作不良引起血糖升高,降低胰岛素的敏感和增加腰部脂肪沉积
"Diabetes not only causes heart disease, but is strongly related to strokes, blindness, kidney failure, amputations. Diabetes is a very serious condition that's highly prevalent in older adults," Carnethon said.
Mercedes Carnethon说“糖尿病不仅引起心脏病,与中风,失明,肾衰,截肢有极大关系,糖尿病在壮年中高度流行是一个十分严重的问题“
Diabetes is a growing worldwide problem, closely tied to obesity. Type 2 diabetes accounts for about 95 percent of all cases.
糖尿病是正在全球增长的问题,与肥胖密切有关,大约95%的病人都是2型糖尿病
The findings point to the importance of doctors screening older adults for depression and, if it's present, for diabetes risk, Carnethon said.
这个发现,指出以示对壮年人的抑郁症的重视,如果出现该病,存在糖尿病的危险 [标签:content1][标签:content2]

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作者:admin@医学,生命科学    2011-02-20 17:11
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