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【JACC】吃鱼有助于减少心血管病死亡率
abstract:
Objectives: The objective of our study was to test the hypothesis that fish or -3 polyunsaturated fatty acids (PUFA) intakes would be inversely associated with risks of mortality from ischemic heart disease, cardiac arrest, heart failure, stroke, and total cardiovascular disease.
Background: Data on associations of dietary intake of fish and of -3 PUFA with risk of cardiovascular disease among Asian societies have been limited.
Methods: We conducted a prospective study consisting of 57,972 Japanese men and women. Dietary intakes of fish and -3 PUFA were determined by food frequency questionnaire, and participants were followed up for 12.7 years. Hazard ratios and 95% confidence intervals were calculated according to quintiles of fish or -3 PUFA intake.
Results: We observed generally inverse associations of fish and -3 PUFA intakes with risks of mortality from heart failure (multivariable hazard ratio [95% confidence interval] for highest versus lowest quintiles = 0.76 [0.53 to 1.09] for fish and 0.58 [0.36 to 0.93] for -3 PUFA). Associations with ischemic heart disease or myocardial infarction were relatively weak and not statistically significant after adjustment for potential risk factors. Neither fish nor -3 PUFA dietary intake was associated with mortality from total stroke, its subtypes, or cardiac arrest. For mortality from total cardiovascular disease, intakes of fish and -3 PUFA were associated with 18% to 19% lower risk.
Conclusions: We found an inverse association between fish and -3 PUFA dietary intakes and cardiovascular mortality, especially for heart failure, suggesting a protective effect of fish intake on cardiovascular diseases.
来源：http://content.onlinejacc.org/cgi/content/abstract/52/12/988?etoc 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领 。 title:Fish, -3 Polyunsaturated Fatty Acids, and Mortality From Cardiovascular Diseases in a Nationwide Community-Based Cohort of Japanese Men and Women
标题：鱼，-3 多不饱和脂肪酸，和基于日本男性和女性人群全国范围内的心血管病死亡率
abstract:
Objectives: The objective of our study was to test the hypothesis that fish or -3 polyunsaturated fatty acids (PUFA) intakes would be inversely associated with risks of mortality from ischemic heart disease, cardiac arrest, heart failure, stroke, and total cardiovascular disease.
摘要：
目的：该研究的目的是检验这样一个假说：鱼或者-3 多不饱和脂肪酸（PUFA）的摄入可能与缺血性心脏病、心脏停博、心力衰竭、中风以及所有心血管疾病的死亡率成负相关。
Background: Data on associations of dietary intake of fish and of -3 PUFA with risk of cardiovascular disease among Asian societies have been limited.
背景：关于亚洲社会从饮食中摄入鱼和3多不饱和脂肪酸和心血管疾病死亡率相关的数据有限。
Methods: We conducted a prospective study consisting of 57,972 Japanese men and women. Dietary intakes of fish and -3 PUFA were determined by food frequency questionnaire, and participants were followed up for 12.7 years. Hazard ratios and 95% confidence intervals were calculated according to quintiles of fish or -3 PUFA intake.
方法：我们指导了一项包括57972名日本男性和女性的前瞻性研究。饮食中摄入的鱼和-3多不饱和脂肪酸通过食物频率调查表来决定，并且参与者被随访12.7年。危害比和95%可信区间根据摄入鱼或-3多不饱和脂肪酸的五分值来计算。
Results: We observed generally inverse associations of fish and -3 PUFA intakes with risks of mortality from heart failure (multivariable hazard ratio [95% confidence interval] for highest versus lowest quintiles = 0.76 [0.53 to 1.09] for fish and 0.58 [0.36 to 0.93] for -3 PUFA). Associations with ischemic heart disease or myocardial infarction were relatively weak and not statistically significant after adjustment for potential risk factors. Neither fish nor -3 PUFA dietary intake was associated with mortality from total stroke, its subtypes, or cardiac arrest. For mortality from total cardiovascular disease, intakes of fish and -3 PUFA were associated with 18% to 19% lower risk.
结果：我们观察到鱼和-3多不饱和脂肪酸的摄入通常与心力衰竭死亡率成负相关（鱼或-3多饱和脂肪酸最高分对最低分的多变量危害比【95%可信区间】分别是0.76【0.53到1.09】和0.58【0.36到0.93】）。与缺血性心脏病或心肌梗死的相关性相对弱些，并且在修正潜在危险因素后没有统计学意义。饮食中摄入鱼和-3多不饱和脂肪酸都与所有中风、它的亚型或者心脏停博无关。对于所有心血管疾病的死亡率而言，鱼和-3多不饱和脂肪酸的摄入可以使风险率降低18%到19%。
Conclusions: We found an inverse association between fish and -3 PUFA dietary intakes and cardiovascular mortality, especially for heart failure, suggesting a protective effect of fish intake on cardiovascular diseases.
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作者:admin@医学,生命科学 2010-10-22 13:09
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