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【medical-news】数以千计的乳腺癌治疗可能路线错
Thousands of breast cancer patients might receive improper medications as a result of inaccurate results for two laboratory tests used to determine the most effective treatments for specific patients, the Wall Street Journal reports. According to the Journal, pharmaceutical companies are "trying to develop more medicines tailored to the individual characteristics of patients and their diseases," but recent studies that have found "problems in testing point to a potential snag for such drugs: They depend on accurate lab results."
The tests used to determine the most effective treatments for specific breast cancer patients are "less straightforward than many traditional lab procedures" and "require pathologists to make judgment calls after looking at tissue through a microscope, rather than giving simple yes-or-no answers," the Journal reports. One of the tests determines whether breast cancer patients have excessive amounts of the protein Her-2 present in their tumors, an indication that they would benefit from Herceptin, manufactured by Genentech.
The second test determines whether breast cancer patients have cell proteins that serve as receptors for estrogen and progesterone -- which can help tumors grow -- an indication that they would benefit from tamoxifen to suppress or block the hormones. 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 粗译：
Inaccurate Lab Tests Might Lead To Inappropriate Treatment Of Breast Cancer
错误的实验室试验可能导致不恰当的乳腺癌治疗方法
Thousands of breast cancer patients might receive improper medications as a result of inaccurate results for two laboratory tests used to determine the most effective treatments for specific patients, the Wall Street Journal reports. According to the Journal, pharmaceutical companies are "trying to develop more medicines tailored to the individual characteristics of patients and their diseases," but recent studies that have found "problems in testing point to a potential snag for such drugs: They depend on accurate lab results."
华尔街日报报道，来自两家实验室有关特定乳腺癌患者有效治疗方法的试验结果可能导致成千上万的患者接受不恰当的治疗。该日报报道，医药公司努力开发更多的针对患者及疾病特征的药物，但最近研究表明这些药物的试验点可能存在一个潜在的严重的问题 我觉得译文中不少翻译为“试验”可能是“实验”吧
不然就不太好理解啊 以人为对象叫试验
以动物为对象叫实验
蓉儿wz wrote:
以人为对象叫试验
以动物为对象叫实验
哦，我认为他们所报道的Lab Tests 就是对乳腺癌患者的癌组织进行免疫组化染色等，然后如果是HER-2阳性或者ER、PR阳性，就相应的给于赫塞汀或者他莫西芬治疗，然后对患者进行随访，观察复发情况、生存率等。
不过，不明白为什么现在报道这个，这些都已经是乳腺癌治疗的规范了啊？怎么还在怀疑？不懂！蓉儿wz wrote:
以人为对象叫试验
以动物为对象叫实验
胭脂 wrote:
我总觉得这里讲的是一些实验室检查
并非真的做实验
已经是大家都知道的了，还在这里写，没意义。 这都早已被证实的事情了 实验和试验我觉得没有必要分得那么清楚，各种场合好像都有互相通用得情况，明白意思应该就行了。hxwuchina wrote:
实验和试验我觉得没有必要分得那么清楚，各种场合好像都有互相通用得情况，明白意思应该就行了。
哈哈，也挺有意思 [标签:content1][标签:content2]阅读本文的人还阅读：
作者:admin@医学,生命科学 2011-05-25 05:14
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