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【编译】研究发现:AIDS鸡尾酒疗法可预防某些癌

研究发现:AIDS鸡尾酒疗法可预防某些癌症

华盛顿(路透社) –“用鸡尾酒药物混合疗法治疗和控制爱滋病病毒也许不仅保持患者健康同时也许还能保护他们免受一些由于传染引起的癌症”星期二法国的研究人员如是说。
药物混合物, 被称为高度活性的抗逆转录病毒法(antiretroviral 疗法)或HAART, 可以抑制致命和几乎是无法杀绝的病毒, 同时有助于病人防止肺炎和其它因HIV病毒破坏免疫系统而引起的传染疾病。 根据来自在法国利昂国际肿瘤研究机构(IARC,附属于WHO)的研究员加利Clifford和他的同事报告:HAART治疗能预防某些癌症,但不是全部。

他们分析了超过7,300 名来自瑞士的HIV 患者纪录,发现那些经HAART治疗的病人发生 Kaposi 肉瘤和non-Hodgkin 淋巴瘤的风险比较那些没有使用HAART的要低好多 。
Kaposi 肉瘤在AIDS病人的发生机率大约是普通健康人的20倍- 这种癌症的明显标志是具有红色皮肤损害,这也是爱滋病人处在病毒感染活跃期的重要标记之一-。AIDS得non-Hodgkin 淋巴瘤(一种淋巴系统的癌症)的情况也与Kaposi 肉瘤类似

不过调查显示这些HIV 患者得其他肿瘤,比如肛门癌, Hodgkin 淋巴瘤, 子宫颈癌, 肝癌, 嘴唇癌, 嘴, 咽喉癌, 非黑瘤皮肤癌等风险似乎没有多大改变,仍高于正常人的机率。这些研究结果和数据是在最近一期美国国家癌症研究院学报上发表的

注:
在过去的研究报道中,鸡尾酒药物混合疗法。在降低AIDS病人死亡率是明显的,但在治疗乙肝,延缓或预防人类的阿尔茨海默氏症和预防肿瘤方面的重要作用还有待于进一步研究证实。

AIDS Cocktails Prevent Cancer, Study Finds
WASHINGTON (Reuters) - Drug cocktails taken to control the AIDS (news - web sites) virus may not only keep patients healthy but may protect them against some cancers caused by the infection, international researchers said on Tuesday.
The drug mixtures, called highly active antiretroviral therapy or HAART, suppress the deadly and incurable virus and help prevent pneumonia and other infections caused when HIV (news - web sites) is left free to destroy the immune system.
HAART also prevents some cancers, according to Gary Clifford of the International Agency for Research on Cancer in Lyon, France, and colleagues. The IARC is associated with the World Health Organization (news - web sites).

They analyzed the records of more than 7,300 Swiss HIV patients and found those on HAART had lower risks of Kaposi's sarcoma and non-Hodgkin's lymphoma compared with those who did not use HAART.
Nonetheless, Kaposi's sarcoma -- a cancer marked by red skin lesions and one of the hallmarks of full-blown AIDS -- was 20 times more common in HIV patients than in the general population. So was non-Hodgkin's lymphoma, a cancer of the lymphatic system.
And the HIV patients still had a higher than usual risk of anal cancer, Hodgkin's lymphoma, cervical cancer, liver cancer, cancer of the lip, mouth, and pharynx, and non-melanoma skin cancer, the researchers reported in the Journal of the National Cancer Institute (news - web sites).

http://news.yahoo.com/news?tmpl=story&ncid=751&e=1&u=/nm/20050315/hl_nm/aids_cancer_dc [标签:content1][标签:content2]

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作者:admin@医学,生命科学    2011-04-26 05:14
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