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【medical-news】研究发现女性更易患多发性硬化
Wed, November 1, 2006
By CP
TORONTO -- Researchers combing over Canadian data on people with multiple sclerosis have discovered women with the disease have inexplicably started to outnumber men by a ratio of more than three to one.
The researchers have also found the gender ratio, rather than being stable as has been commonly thought, has been rising almost constantly for at least 50 years.
It has jumped from about 1.9 women for every man for those born in the 1930s, to 3.2 women for every man for those born around 1980.
The rise over this long period has been so pronounced it has made multiple sclerosis an overwhelmingly female-dominated disease, even though it wasn't originally.
Until the 1940s most doctors believed there was no gender-based difference in the incidence rate, and it was only in the 1950s and 1960s that doctors began to notice that the disease was more common in women.
The new findings appear in the November edition of the journal Lancet Neurology.
The researchers who conducted the study of the Canadian multiple sclerosis data speculate something new has arisen in the environment in the past half-century to make women far more likely to develop the disease.
They don't know why it doesn't seem to affect men.
If multiple sclerosis rates are rising among women because of an environmentally induced cause, the discovery of what this might be could possibly suggest an avenue for preventing the often disabling disease.
"What is going on here is something presumably that is preventable," said George Ebers, a professor in the department of clinical neurology at the University of Oxford in Britain and lead author of the study. "We just need to find out what it is in the environment. Because it has to be environmental; your genes don't change over two generations, three generations."
Ebers spent 22 years at London's University of Western Ontario before leaving for Britain in 1999.
Scientists don't know what causes multiple sclerosis, although it's more prevalent in wealthy countries. Canada has one of the highest rates in the world. It's also above normal in Northern Europe, which has led to speculation the cause may have something to do with vitamin D. Levels of the vitamin fall off in northern countries during the winter months because sunlight isn't intense enough to enable people to make it in their skins.
http://lfpress.ca/newsstand/News/National/2006/11/01/2196756-sun.html 认领了。 Females more prone to MS, research finds
Wed, November 1, 2006
By CP
研究发现女性更易患多发性硬化
2006年11月1日，周三
TORONTO -- Researchers combing over Canadian data on people with multiple sclerosis have discovered women with the disease have inexplicably started to outnumber men by a ratio of more than three to one.
多伦多--研究员在整理加拿大的多发性硬化患者数据时发现，开始出现女性患者较男性为多的现象，原因不很明确。目前女性患者数目为男性的3倍多。
The researchers have also found the gender ratio, rather than being stable as has been commonly thought, has been rising almost constantly for at least 50 years.
此外，研究者还发现该性别比例是近50年里不断上升的结果，并非我们认为的那样原来就如此。
It has jumped from about 1.9 women for every man for those born in the 1930s, to 3.2 women for every man for those born around 1980.
19世纪30年代出生的人群中，该病的男女比例为1.9：1，而对于出生于1980年左右的人群中，该比例骤增到了3.2：1。
The rise over this long period has been so pronounced it has made multiple sclerosis an overwhelmingly female-dominated disease, even though it wasn't originally.
这段较长时间内男女患者比例的这种变化使得多发性硬化成了常见于女性的疾病，但多年以前并非如此。
Until the 1940s most doctors believed there was no gender-based difference in the incidence rate, and it was only in the 1950s and 1960s that doctors began to notice that the disease was more common in women.
19世纪的40年代以前大多数医生认为该病的发病率并没有性别差异，而到了19世纪50年代和60年代，医生们才开始注意到多发性硬化更多见于女性。
The new findings appear in the November edition of the journal Lancet Neurology.
Lancet Neurology杂志的11月版中提到了此项新的发现。
The researchers who conducted the study of the Canadian multiple sclerosis data speculate something new has arisen in the environment in the past half-century to make women far more likely to develop the disease.
进行加拿大多发性硬化患者数据研究的人员推测在这过去的半个世纪，可能在环境中出现了某种因素，导致了女性更易罹患此病。
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作者:admin@医学,生命科学 2011-03-14 05:11
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