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【medical-news】腿长也是祸？研究发现长得高的人
Friday, March 07, 2008
Tall women and those who put on weight are more likely to develop deadly melanoma, according to a study by Australian scientists; it is being reported by news.com.au.
Researchers are puzzled by the results of a major review of skin cancer patterns that found women's body size appears to be linked to their disease risk.
The team from the Queensland Institute of Medical Research reviewed eight studies involving almost 5,000 women, including half with melanoma.
They found that the tallest one-quarter of individuals in the study were 30 percent more likely to have melanoma than shorter women.
"We found this risk greater among women less than 50 years of age," said study leader Dr. Catherine Olsen, who collaborated with researchers in the U.S., U.K., Canada and Italy.
Other studies have suggested that taller women are also more likely to develop breast and colon cancer.
The researchers, writing in the International Journal of Cancer, said the association between height and cancer risk was not clear.
Height could be related to hormones that may play a role in the development of cancer, they said.
It could also be a marker for extra calories consumed in growth periods like adolescence, a suggested cancer risk seen in animal research.
Olsen said it might even be that taller women spend more time in the sun, although there is little proof of this.
The study, which involved 2,083 women with melanoma and 2,782 healthy controls, also found that putting on 4 pounds or more boosted melanoma risk by 50 percent. Olsen said weight gain could contribute to risk by affecting hormone metabolism.
The team called for similar studies to identify the links between body size and cancer risk in men.
Cancer Council Australia Chief Executive Professor Ian Olver said it would be difficult to establish the factors in height and weight gain that were linked to disease, but it was likely related to a third factor such as hormones, diet or increased body surface area.
Melanoma is most prevalent in Australia and New Zealand.
The strongest risk factors are severe and repeated sun exposure, and pale skin, as well as a rare genetic association, Olver said.
http://www.foxnews.com/story/0,2933,335903,00.html 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领 Friday, March 07, 2008
Tall women and those who put on weight are more likely to develop deadly melanoma, according to a study by Australian scientists; it is being reported by news.com.au.
据news.com.au 报道，澳大利亚科学家的一项研究显示：个子高的女性和那些体重比较大的人群罹患致命的黑色素瘤的可能性大。
Researchers are puzzled by the results of a major review of skin cancer patterns that found women's body size appears to be linked to their disease risk.
研究人员对皮肤癌的发病率与女性的体形大小有关感到困惑。
The team from the Queensland Institute of Medical Research reviewed eight studies involving almost 5,000 women, including half with melanoma.
Queensland医学研究所的研究小组回顾了包括了大约5,000名女性的八项研究，其中有一半患有黑色素瘤。
They found that the tallest one-quarter of individuals in the study were 30 percent more likely to have melanoma than shorter women.
他们发现在这项研究中身高最高的四分之一个体罹患黑色素瘤的几率比她们矮的个体高出30％。
"We found this risk greater among women less than 50 years of age," said study leader Dr. Catherine Olsen, who collaborated with researchers in the U.S., U.K., Canada and Italy.
同美国、英国、加拿大、意大利的学者合作者，此项研究的领导者， Catherine Olsen博士说：“我们发现这种风险在年龄小于50岁的女性中相当普遍。”
Other studies have suggested that taller women are also more likely to develop breast and colon cancer.
另外的研究还发现，个子高的女性还更容易罹患乳腺癌和结肠癌。
The researchers, writing in the International Journal of Cancer, said the association between height and cancer risk was not clear.
研究人员在《国际癌症杂志》上写道，关于身高和癌症之间的相关性还未被阐明。
Height could be related to hormones that may play a role in the development of cancer, they said.
他们说，与身高相关的荷尔蒙可能在癌症的发生过程中起关键作用。
It could also be a marker for extra calories consumed in growth periods like adolescence, a suggested cancer risk seen in animal research.
关于癌症危险性的动物实验显示，这还可能是如青春期等发育阶段额外卡路里耗费的一个标志。
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作者:admin@医学,生命科学 2011-02-15 05:14
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