【medical-news】Scientists find inflammation immune cell sw
Scientists find inflammation immune cell switch
By Kate Kelland
updated 1/16/2011 1:03:11 PM ET
LONDON — Scientists have found a protein that acts as a "master switch" to determine whether certain white blood cells will boost or dampen inflammation, a finding that may help the search for new drugs for rheumatoid arthritis.
Many patients with rheumatoid arthritis are treated with a class of drugs known as tumor necrosis factor (TNF) inhibitors made by various drug firms including Abbott Laboratories, Merck & Co, Pfizer and Amgen
But around 30 percent of patients don't respond to anti-TNF drugs, so experts say there is an urgent need to develop more widely effective treatment options.
In this study, scientists from Imperial College in London found that a protein called IRF5 acts as a molecular switch that controls whether certain white blood cells, known as macrophages, will promote or inhibit inflammation. 【medical-news】死亡使者分子在脊髓损伤后引起炎症反应,防止...发表时间：2010-3-19回帖数：0http://www.sciencedaily.com/releases/2010/03/100303092359.htm sciencedaily (mar. 6,... immune cells to the injured spinal cord and not by programmed cell death. blocking ...www.ruanjian520.com/thread-... - 2010-03-19-快照-【medical-news】死亡使者分子在脊髓损伤后引起炎症反应,防止..." 【medical-news】Insulin-producing cells can renegerate in diab发表时间：2010-4-8回帖数：0replacements for some diabetics' missing insulin-producing cells might be found in... could figure out how to stop the immune system attack and reduce inflammation in ...www.ruanjian520.com/thread-... - 2010-04-08-快照-【medical-news】Insulin-producing cells can renegerate in diab" 清华大学生命科学学院上目录导师简介(44人)文件类型:DOC/Microsoft Word- 文字版Columbia University Medical Center 2008年底 副教授 清华大学生命科学学院结构生物... programmed cell death during the plant innate immune response, Cell, 121(4), 567-...www.nibs.ac.cn/...91124_04.doc-2011-01-01-生命科学学院上目录导师简介(44人)"[标签:content2]
作者:admin@医学,生命科学 2011-01-17 12:25