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【medical-news】疲劳是癌症患者生活质量下降的主

Fatigue harms cancer patients' quality of life

Reuters Health

Thursday, December 21, 2006

NEW YORK (Reuters Health) - Among women diagnosed with breast cancer, fatigue is the symptom most strongly associated with a worse overall quality of life, German researchers report.

The influence of fatigue "by far" exceeded that of symptoms such as pain, nausea, and sleeping problems, Dr. Volker Arndt of the German Cancer Research Center in Heidelberg and colleagues found.

While cancer patients' symptoms are understood to have an impact on their quality of life, few researchers have attempted to separate out the individual effects of each symptom, they note in the journal Cancer.

To investigate, Arndt and colleagues surveyed 314 women one year after they were diagnosed with breast cancer, using a questionnaire that gauged both quality of life and levels of symptoms.

The most common symptoms the women reported were fatigue, sleeping problems, pain, and symptoms involving the arms, the researchers found.

Fatigue was the most important factor determining a woman's overall quality of life, the researchers found, accounting for 30 percent to 50 percent of variability in quality of life scores.

Little is known about the causes of fatigue in cancer patients, and there is a "profound communication gap" between doctors and patients regarding cancer-related fatigue, Arndt and colleagues write.

Suggested treatments include "mild physical exercise, sleep hygiene and attention-restoring activities," they add, and while therapy with stimulant drugs, transfusion of red blood cells, or treatment with red blood cell-boosting erythropoietin have all been suggested as well, there is little evidence on their effectiveness.

"These findings suggest that efforts to reduce specifically the burden of fatigue may be very promising approaches to enhance quality of life in breast cancer survivors," Arndt and colleagues conclude.

SOURCE: Cancer, November 15, 2006.

http://www.nlm.nih.gov/medlineplus/news/fullstory_42918.html 本人已认领该文编译,48小时后若未提交译文,请其他战友自由认领 Fatigue harms cancer patients' quality of life
疲劳是癌症患者生活质量下降的主要原因
Reuters Health
路透社健康
Thursday, December 21, 2006
2006年12月21日 星期四
NEW YORK (Reuters Health) - Among women diagnosed with breast cancer, fatigue is the symptom most strongly associated with a worse overall quality of life, German researchers report.
纽约(路透社健康) 那些被诊断为乳腺癌的妇女,疲劳是整体生活质量下降的最主要症状,德国研究者报导。
The influence of fatigue "by far" exceeded that of symptoms such as pain, nausea, and sleeping problems, Dr. Volker Arndt of the German Cancer Research Center in Heidelberg and colleagues found.
疲劳的影响“到目前为止”超过了例如疼痛、恶心、和睡眠问题等症状,位于Heidelberg的德国癌症研究中心(German Cancer Research Center)的Dr. Volker 及其同事报导。
While cancer patients' symptoms are understood to have an impact on their quality of life, few researchers have attempted to separate out the individual effects of each symptom, they note in the journal Cancer.
虽然明白癌症患者的症状影响他们的生活质量,但很少研究者曾试图去分离每个症状的个体效应,他们在癌症杂志写道。
To investigate, Arndt and colleagues surveyed 314 women one year after they were diagnosed with breast cancer, using a questionnaire that gauged both quality of life and levels of symptoms.
为了进行研究,Arndt和他的同事们调查了314名在1年内被诊断为乳腺癌的妇女,使用调查表评估影响生活质量和水平的症状。
The most common symptoms the women reported were fatigue, sleeping problems, pain, and symptoms involving the arms, the researchers found.
研究者发现,这些妇女报告最常见的症状是疲劳、睡眠问题、疼痛和牵涉到上肢的症状。
Fatigue was the most important factor determining a woman's overall quality of life, the researchers found, accounting for 30 percent to 50 percent of variability in quality of life scores.
疲劳决定妇女整体生活质量的最主要因素,研究者发现,根据是疲劳的分数占生活质量评分的30%~50%。
Little is known about the causes of fatigue in cancer patients, and there is a "profound communication gap" between doctors and patients regarding cancer-related fatigue, Arndt and colleagues write.
对引起癌症患者疲劳的原因我们知之甚少,在医师与癌症患者之间对癌症-相关性疲劳存在着“深深的沟通代沟”,Arndt和他的同事写道。
Suggested treatments include "mild physical exercise, sleep hygiene and attention-restoring activities," they add, and while therapy with stimulant drugs, transfusion of red blood cells, or treatment with red blood cell-boosting erythropoietin have all been suggested as well, there is little evidence on their effectiveness.

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作者:admin@医学,生命科学    2011-03-24 18:59
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