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【medical-news】牙龈疾病与糖尿病息息相关
NEW YORK (Reuters Health) - People with moderate to severe gum disease may have an elevated risk of developing type 2 diabetes, the results of a new study suggests.
Researchers found that among nearly 9,300 U.S. adults who were followed for 17 years, those who began the study with gum disease were more likely to develop diabetes later on. Men and women with moderate gum disease had twice the risk of diabetes as those with healthy gums, while substantial tooth loss was linked to a 70 percent higher risk.
The findings, published in the journal Diabetes Care, do not prove that gum disease causes diabetes in some people. But the study is the first to show such a temporal association between the two conditions; the relationship between diabetes and gum disease is well-known, but it has traditionally been assumed that gum disease is solely a consequence of diabetes.
"The pertinent finding was our observation that periodontal disease can precede the onset of overt type 2 diabetes," lead researcher Dr. Ryan T. Demmer, of Columbia University in New York, told Reuters Health.
He added, however, that more studies are needed both to prove that gum disease directly contributes to type 2 diabetes, and, from there, that treating the dental problem can prevent diabetes.
"It would be inappropriate, based on our findings, to definitively say that better oral health will reduce an individual's risk of diabetes development," Demmer said.
Still, the findings are in line with research suggesting that gum disease is a risk factor for heart disease and stroke. Gum disease arises from bacterial infection, and it is thought that chronic, systemic inflammation in response to the bacteria may contribute to cardiovascular disease.
In theory, this could also explain the link to diabetes. Demmer noted that inflammatory molecules could, for instance, affect the body's sensitivity to the blood-sugar-regulating hormone insulin. For now, though, that is a theory.
SOURCE: Diabetes Care, July 2008.
http://www.reuters.com/article/healthNews/idUSTON17323920080721 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 Gum disease tied to diabetes risk
牙龈疾病与糖尿病风险相关
NEW YORK (Reuters Health) - People with moderate to severe gum disease may have an elevated risk of developing type 2 diabetes, the results of a new study suggests.
纽约（路透 健康）-患有中度到重度牙龈疾病的人群，可能比普通人群增加患2型糖尿病的风险，一项新的研究显示。
Researchers found that among nearly 9,300 U.S. adults who were followed for 17 years, those who began the study with gum disease were more likely to develop diabetes later on. Men and women with moderate gum disease had twice the risk of diabetes as those with healthy gums, while substantial tooth loss was linked to a 70 percent higher risk.
研究者在对9300名美国成年人17年随访后发现，开始这项研究时患有牙龈疾病的人随后更有可能发生糖尿病。患有牙龈疾病的男性和女性是牙龈健康的人群患有糖尿病风险的两倍，而牙实质丢失可能增加70%的风险。
The findings, published in the journal Diabetes Care, do not prove that gum disease causes diabetes in some people. But the study is the first to show such a temporal association between the two conditions; the relationship between diabetes and gum disease is well-known, but it has traditionally been assumed that gum disease is solely a consequence of diabetes.
结果刊登在糖尿病期刊，没有证明在某些人中牙龈疾病会引起糖尿病。但是这项研究是第一次指出这两种状况之间的相互影响；糖尿病和牙龈疾病之间的关系是众所周知的，传统的假定认为牙龈疾病仅仅是糖尿病的继发病。
"The pertinent finding was our observation that periodontal disease can precede the onset of overt type 2 diabetes," lead researcher Dr. Ryan T. Demmer, of Columbia University in New York, told Reuters Health.
“相关发现来源于我们观察到牙周疾病可以先于2型糖尿病发生，”纽约哥伦比亚大学首席研究员Ryan T. Demmer博士告诉路透 健康。
He added, however, that more studies are needed both to prove that gum disease directly contributes to type 2 diabetes, and, from there, that treating the dental problem can prevent diabetes.
他还说，然而我们需要进行更多的研究来证明牙龈疾病直接导致2型糖尿病，和因此处理牙齿问题能够预防糖尿病。
"It would be inappropriate, based on our findings, to definitively say that better oral health will reduce an individual's risk of diabetes development," Demmer said.
“基于我们的研究，肯定地认为更好的口腔健康将减少个体发生糖尿病的风险是不合适的，”Demmer说。
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作者:admin@医学,生命科学 2011-08-29 17:14
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