（Science News －－编译 ）全面的治疗能改善心衰病
心衰病人认知功能障碍很常见, 过去一直认为是心源性痴呆 , 通过治疗这些病人的合并症比如电解质紊乱，贫血和 高血糖症，他们的认知功能可以得到改善。
在对 16,913名病人其中有1511名心衰病人包括526名(35%) 表现认知功能障碍的研究后发现， 低蛋白、低钠和低钾水平，高血糖，贫血和心脏收缩的血压水平这些因素均与感知功能障碍有关。
领导这项研究的Giuseppe Zuccalà博士 说， 心衰病人认知功能障碍并不单纯是理论问题，…,患有认知功能障碍的老年心衰病人的死亡率增加，生活质量严重下降 。通过 控制血糖，血钾和血色素水平能改善认知状况。 这更证明了老年心衰病人全面治疗的必要性。
Comprehensive treatment improves cognitive impairment in heart failure patients
30 Apr 2005
It is common for patients in heart failure to show cognitive dysfunction, known in the past as "cardiogenic dementia." However, by evaluating and treating some coexisting conditions observed in these patients, such as salt imbalances, anemia and hyperglycemia, their cognitive functions may improve independently of the underlying cardiac problems.
In a study published in the current issue of The American Journal of Medicine, researchers from the Catholic University, Rome, Italy and Wake Forest University, Winston-Salem, North Carolina examined records from 16,913 patients. Of these, 1511 suffered heart failure and 526 (35%) also exhibited cognitive dysfunction. Low serum albumin, sodium and potassium levels, hyperglycemia, anemia, and systolic blood pressure levels were independently associated with cognitive impairment.
According to Dr. Giuseppe Zuccalà, "The issue of cognitive impairment associated with heart failure does not represent a mere academic question…Among older patients with heart failure, cognitive dysfunction has been associated with a fivefold increase in the risk of mortality, and a sixfold increase in the probability of dependence for the activities of daily living."
Treating cognitive dysfunction independently may yield benefits. Dr. Zuccalà continues, "Our data indicate that normalization of glucose, potassium, and hemoglobin levels during hospital stay is associated with increased cognitive performance at discharge. This confirms the need for a comprehensive approach to heart failure in older populations."
The study is reported in "Correlates of Cognitive Impairment among Patients with Heart Failure: Results of a Multicenter Survey" by Giuseppe Zuccalà, Emanuele Marzetti, Matteo Cesari, Maria R. Lo Monaco, Livia Antonica, Alberto Cocchi, Pierugo Carbonin, Roberto Bernabei. This article appears in The American Journal of Medicine, Volume 118, Number 5 (May 2005), published by Elsevier.
xiaowenok edited on 2005-04-30 12:07 [标签:content1][标签:content2]
作者:admin@医学,生命科学 2011-04-07 05:11