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【Nature】推介论文：抗炎免疫细胞

After a heart attack, a type of immune cell can lessen the damaging inflammatory response in the organ by recognizing cells undergoing apoptosis, or programmed cell death. To mimic this protective effect, Smadar Cohen at Ben-Gurion University of the Negev in Beer-Sheva, Israel, and her group designed a liposome — a lipid-based bubble — with the molecule phosphatidylserine on its surface. This is abundant on apoptotic cells, and prompts the immune system's macrophage cells to secrete anti-inflammatory factors.

The authors showed that mouse macrophages took up the liposomes and shifted to an anti-inflammatory mode. Rats injected with liposomes after an induced heart attack showed an accumulation of macrophages in the damaged area after four days (pictured with arrow). After four weeks, the rats also had a greater density of heart blood vessels than untreated animals and less remodelling of their left ventricle, a common after-effect of a heart attack.

原文
http://www.pnas.org/content/108/5/1827 本人已认领该文献编译，48小时如仍未提交，请其他战友自由认领。 医药生命科学动态跟踪 - 丁香园论坛 - 医学/药学/生命科学论坛丁香园论坛-医学/药学/生命科学论坛 医药生命科学动态跟踪 super19830102 【哲学版活... 刊载丁香园调查结果:医者险境谁来解? 出路何在? 【Nature】推介论文:抗炎免疫细胞 【...news.dxy.cn/-2天前-快照-医药生命科学动态跟踪 - 丁香园论坛 - 医学/药学/生命科学论坛" 乙烯基吡咯烷酮(NVP)和聚乙烯吡咯烷酮(PVP)生产项目文件类型:DOC/Microsoft Word- 文字版联系地址:厦门大学生命科学学院 养生堂北京万泰生物药业有限公司 联系人:夏宁邵(厦门... 抗血栓、抗炎症和抗过敏等作用. Nature上报道有效延长老鼠寿命所需白藜芦醇用量为...www.xiangankj.gov.cn/...推介.doc-2011-01-20-相聚长三角海外嘉宾项目(共177个项目) ... 江苏侨网项目联系人 施海潮 工作单位及职务 索福拉日本株式会社主任研究员,日本生命科学协会... 随时自动杀灭体内的前列腺癌细胞.预计药理学有效率应该在90%以上.预计免疫记忆的...www.jsqw.com/...453109087.aspx-2009-03-03-快照-[标签:content2]

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作者:admin@医学,生命科学    2011-02-07 00:03
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