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【medical-news】行男性包皮环切术可预防性传播疾
Dr. Robert C. Bailey from the University of Illinois at Chicago and his team from Kenya reported 42-month follow-up results on the protective effects of male circumcision. They had previously reported encouraging results after 24 months of their randomized trial, which was stopped in December 2006 due to significant protective benefits, with the controls also being offered circumcision.
The cumulative incidence of HIV infection over 42 months among circumcised men was 2.6% as compared to 7.4% among controls, the researchers observed. The protective effect of circumcision was 64% (i.e., relative risk of infection, 0.36), they noted.
Male circumcision provides a sustained protective effect against HIV, Dr. Bailey's team concludes.
In another study, Dr. Bertran Auvert from Universite de Versailles, France and his team from South Africa analyzed the protective effect of male circumcision against other sexually transmitted infections.
In their randomized study of men aged between 18 and 24, the prevalence of human papilloma virus and trichomonas vaginalis was lower in the circumcised group with odds of 0.57 and 0.54, respectively, after 21 months follow up, they report. There was no effect on gonorrhea rates.
"Circumcision could therefore be an indirect way of limiting the risk of genital cancers caused by HPV in women," Dr. Auvert said during a related press conference.
Male circumcision can prevent between 2 to 8 million new HIV infections in the sub-Saharan Africa, resulting in savings of around $2 billion over the next 20 years, Dr. Auvert said.
Male circumcision is safe, with minimal side effects, and can be promoted as a universal preventive measure against HIV, Dr. Dirk Taljaard, one of the co-authors of the second study told Reuters Health.
"The studies of male circumcision have opened up a whole new era in the fight against AIDS: we now potentially have a new method of prevention," Professor Jean-Francois Delfraissy concluded during the press conference. 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 行男性包皮环切术可以预防性传播疾病
MEXICO CITY (Reuters Health) Aug 07 - Male circumcision has a protective effect against HIV, human papilloma virus and trichomonas vaginalis infections, researchers reported at the International AIDS Conference here.
路透社健康报墨西哥城8月7日报道—在当地召开的国际艾滋病大会上有研究者报告说，男性包皮环切术对人类免疫缺陷病毒（HIV），人类乳头状瘤病毒（HPV）和阴道毛滴虫感染有保护作用。
Dr. Robert C. Bailey from the University of Illinois at Chicago and his team from Kenya reported 42-month follow-up results on the protective effects of male circumcision. They had previously reported encouraging results after 24 months of their randomized trial, which was stopped in December 2006 due to significant protective benefits, with the controls also being offered circumcision.
芝加哥伊利诺伊州立大学的Robert C. Bailey博士及其团队报道了一项在肯尼亚进行的关于男性包皮环切术保护效应的随访研究，该研究共持续了42个月。他们在之前还进行过另一项持续了24个月随机实验，结论令人鼓舞，该实验表明包皮环切术具有明显的保护作用，在对照组也施行了环切术之后（基于伦理学顾虑），该随机实验于2006年12月被终止。
The cumulative incidence of HIV infection over 42 months among circumcised men was 2.6% as compared to 7.4% among controls, the researchers observed. The protective effect of circumcision was 64% (i.e., relative risk of infection, 0.36), they noted.
在42个月的研究中，据研究者观察，包皮环切术组HIV感染累计发病率为2.6%，而对照组累积发病率为7.4%。包皮环切术的保护率达到了64%（例如，感染的相对危险度为0.36），他们解释说。
Male circumcision provides a sustained protective effect against HIV, Dr. Bailey's team concludes.
男性包皮环切术对HIV感染提供了一种持久的保护效应，Bailey博士的研究团队总结道。
In another study, Dr. Bertran Auvert from Universite de Versailles, France and his team from South Africa analyzed the protective effect of male circumcision against other sexually transmitted infections.
在另一项研究中，来自法国凡尔赛大学的Bertran Auvert博士及其来自非洲南部的研究团队分析了男性包皮环切术对其它性传播疾病的保护效应。
In their randomized study of men aged between 18 and 24, the prevalence of human papilloma virus and trichomonas vaginalis was lower in the circumcised group with odds of 0.57 and 0.54, respectively, after 21 months follow up, they report. There was no effect on gonorrhea rates.
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作者:admin@医学,生命科学 2011-07-21 07:25
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