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【medical-news】勃起功能障碍患者发生帕金森病风
Wed Dec 26, 2007 9:11am EST
NEW YORK (Reuters Health) - Results of a study suggest an association between erectile dysfunction and an increased risk of developing Parkinson's disease.
The autonomic nervous system, which regulates involuntary bodily functions like heart rate and digestion, is often affected in Parkinson's disease, and erectile function, which is controlled by the autonomic system, is commonly compromised, the study team notes in a report.
"An important question," according to Dr. Xiang Gao, of Harvard School of Public Health, Boston, Massachusetts, and colleagues, "is whether erectile dysfunction precedes the onset of motor symptoms of Parkinson's disease."
They examined the question using data from the Health Professionals Follow-up Study. A total of 32,616 men free of Parkinson's disease in 1986 were included in the present study. In 2000, the men completed a questionnaire with questions on erectile dysfunction in different time periods. The relation between erectile dysfunction before 1986 and Parkinson's disease risk from 1986 to 2002 was analyzed.
During the 16 years' follow-up, 200 men were diagnosed with Parkinson's disease.
Compared to men who reported very good erectile function before 1986, those who reported erectile dysfunction had a significant 3.8-fold increased risk of developing Parkinson's disease, the investigators report.
"We further explored possible interactions of erectile function with age, body mass index, cigarette smoking, caffeine intake, and the presence of diabetes during follow-up," Gao's team explains. "None of these interactions was significant."
These findings, they conclude, support the hypothesis that the autonomic nervous system "may have been impaired years before Parkinson's disease is clinically recognizable."
SOURCE: American Journal of Epidemiology, December 2007.
http://www.reuters.com/article/healthNews/idUSLAU64947620071226 Erectile dysfunction may precede Parkinson's
Wed Dec 26, 2007 9:11am EST
勃起功能障碍可能先于帕金森病
2007年12月26日，星期三，美国东部标准时间上午9:11
NEW YORK (Reuters Health) - Results of a study suggest an association between erectile dysfunction and an increased risk of developing Parkinson's disease.
路透社，纽约----一项新的研究表明勃起功能障碍和帕金森病危险性增加具有相关性。
The autonomic nervous system, which regulates involuntary bodily functions like heart rate and digestion, is often affected in Parkinson's disease, and erectile function, which is controlled by the autonomic system, is commonly compromised, the study team notes in a report.
研究小组在报告中称，调节不随意机体活动如心率和消化的自主神经系统在帕金森病中常被累及，而受自主神经系统控制的勃起功能也通常受影响，
"An important question," according to Dr. Xiang Gao, of Harvard School of Public Health, Boston, Massachusetts, and colleagues, "is whether erectile dysfunction precedes the onset of motor symptoms of Parkinson's disease."
马萨诸塞州波士顿哈佛公共卫生学院的Xiang Gao博士和他的同仁说：“一个重要的问题是勃起功能障碍是否在帕金森病运动性症状之前出现。”
They examined the question using data from the Health Professionals Follow-up Study. A total of 32,616 men free of Parkinson's disease in 1986 were included in the present study. In 2000, the men completed a questionnaire with questions on erectile dysfunction in different time periods. The relation between erectile dysfunction before 1986 and Parkinson's disease risk from 1986 to 2002 was analyzed.
他们利用健康专业随访研究的数据对这个问题进行了研究。1986年共计32,616名无帕金森病的男性被纳入当前的研究。在2000年，在不同的时间段对入选者完成了关于勃起功能障碍的问卷调查。并分析了1986年前已有勃起功能障碍和1986年至2002年间患帕金森病危险性之间的联系。
During the 16 years' follow-up, 200 men were diagnosed with Parkinson's disease.
在16年的随访中，200人被诊断为帕金森病。
Compared to men who reported very good erectile function before 1986, those who reported erectile dysfunction had a significant 3.8-fold increased risk of developing Parkinson's disease, the investigators report.
研究者报告，与1986年前勃起功能良好的男性相比，勃起功能障碍者患帕金森病的危险性增加了3.8倍。
"We further explored possible interactions of erectile function with age, body mass index, cigarette smoking, caffeine intake, and the presence of diabetes during follow-up," Gao's team explains. "None of these interactions was significant."
Gao的团队解释说：“我们进一步探讨了随访中勃起功能和年龄、体重指数、吸烟、饮咖啡、糖尿病之间的关系，但是没有一个是显著的。”
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作者:admin@医学,生命科学 2011-01-11 05:14
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