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【bio-news】老年痴呆患者经常接受脑部电刺激有利
Electrical stimulation of the brain may improve memory and recognition in elderly people who suffer from Alzheimer's disease, results of a study hint.
"Our preliminary data on Alzheimer's disease patients are promising as we observed beneficial effects after a single session of transcranial direct current stimulation," Dr. Alberto Priori from the University of Milan told Reuters Health, "suggesting that chronic daily application might induce even greater improvement."
"Our studies encourage broader research programs using different stimulation protocols and longer clinical follow-up to clarify the impact this therapy might have on patients' daily functional activities," Priori added.
Priori and colleagues investigated whether electrical stimulation applied over an area at the side of the brain called the temporoparietal cortex could improve recognition memory in 10 patients with Alzheimer's disease.
The treatment significantly improved word recognition memory accuracy, they found report, whereas sham treatment had no impact on memory.
The results were similar after correcting memory performance for guessing, the report indicates.
"Interestingly," the investigators say, the electrical stimulation-induced improvement in the word recognition test observed in patients with Alzheimer's disease is comparable to the 16 percent improvement induced by long-term treatment with cholinesterase inhibitors - drugs currently used to treat early memory problems in patients with dementia.
"We are assessing possible long-lasting effects of (electrical stimulation) in Alzheimer's disease patients using repeated session protocols in a larger sample with longer clinical follow-up," Priori said.
"We believe that the best results, especially in Alzheimer's disease patients, could be obtained by combining transcranial direct current stimulation with cognitive rehabilitation," Priori added.
http://www.reuters.com/article/healthNews/idUSPAT26414720080822 Brain stimulation improves memory in Alzheimer's
老年痴呆患者(阿尔茨海默氏症)经常接受脑部电刺激有利于提高记忆力
Electrical stimulation of the brain may improve memory and recognition in elderly people who suffer from Alzheimer's disease, results of a study hint.
一项研究的结果提示，电刺激脑可改善阿尔茨海默病老年患者的记忆和认知的功能。
"Our preliminary data on Alzheimer's disease patients are promising as we observed beneficial effects after a single session of transcranial direct current stimulation," Dr. Alberto Priori from the University of Milan told Reuters Health, "suggesting that chronic daily application might induce even greater improvement."
米兰大学的Dr. Alberto Priori 告诉路透社健康报“我们的初步数据，对老人痴呆症患者是大有希望的，因为我们单一的时间经直流电流刺激后观察到有利影响，这表明长期每日应用程序可能会有更大的改善“
"Our studies encourage broader research programs using different stimulation protocols and longer clinical follow-up to clarify the impact this therapy might have on patients' daily functional activities," Priori added.
“我们的研究，鼓励更广泛的研究计划即使用不同的刺激方案和长期的临床随访来证明其效应，这种疗法可能对病人的日常功能性活动， 起到治疗作用”
Priori and colleagues investigated whether electrical stimulation applied over an area at the side of the brain called the temporoparietal cortex could improve recognition memory in 10 patients with Alzheimer's disease
Priori和他的同事调查在10名阿尔茨海默病病人用电刺激的应用超过称为颞皮层的大脑侧的一区是否可提高识别记忆。
The treatment significantly improved word recognition memory accuracy, they found report, whereas sham treatment had no impact on memory.
他们发现治疗后明显改善识别记忆的准确性，而对照治疗组并没有影响记忆。
The results were similar after correcting memory performance for guessing, the report indicates.
该报告提示纠正猜测的记忆表现形式后，结果是差不多的。
"Interestingly," the investigators say, the electrical stimulation-induced improvement in the word recognition test observed in patients with Alzheimer's disease is comparable to the 16 percent improvement induced by long-term treatment with cholinesterase inhibitors - drugs currently used to treat early memory problems in patients with dementia.
“有趣的是， ”研究者说，在阿尔茨海默病患者电刺激诱导的词识别试验改善的比较， 16 ％的改善长期胆碱酯酶抑制剂的治疗-目前用于治疗早期记忆问题的痴呆患者的药物。
"We are assessing possible long-lasting effects of (electrical stimulation) in Alzheimer's disease patients using repeated session protocols in a larger sample with longer clinical follow-up," Priori said.
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作者:admin@医学,生命科学 2011-02-27 05:14
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