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【medical-news】联合用药可缓解肺动脉高压
FRIDAY, Dec. 1 (HealthDay News) -- A combination therapy of two drugs -- inhaled iloprost and bosentan -- appears to improve the condition of patients with pulmonary arterial hypertension (PAH), a debilitating and potentially fatal disease characterized by a progressive narrowing of blood vessels in the lungs.
Dr. Vallerie V. McLaughlin, of the University of Michigan Medical Center, and nine colleagues studied 65 PAH patients who were being treated with bosentan, an endothelin receptor antagonist that helps boost blood flow in the lungs.
Of those patients, 32 were selected to receive inhaled iloprost (a prostacyclin analog) along with bosentan, while the remainder took a placebo and bosentan.
By the end of the 12-week study, all the patients who received the bosentan-iloprost therapy were able to walk 98 feet further during a six-minute walk test, and 11 of them showed improvement in a measurement of how severely they were affected by PAH.
In addition, none of the patients who received the bosentan-iloprost therapy experienced clinical deterioration over the course of the study.
The findings are published in the first issue for December of the American Journal of Respiratory and Critical Care Medicine.
Symptoms of PAH, which has no known cause, include shortness of breath following exercise, excessive fatigue, weakness, dizziness and fainting. The symptoms tend to grow worse over time.
-- Robert Preidt
SOURCE: American Thoracic Society, news release, Dec. 1, 2006
http://www.medicinenet.com/script/main/art.asp?articlekey=77879 本人已认领该文编译，48小时后若未提交译文，请其他战友自由认领。 Combination Therapy Eases Pulmonary Arterial Hypertension
联合用药可缓解肺动脉高压
FRIDAY, Dec. 1 (HealthDay News) -- A combination therapy of two drugs -- inhaled iloprost and bosentan -- appears to improve the condition of patients with pulmonary arterial hypertension (PAH), a debilitateing and potentially fatal disease characterized by a progressive narrowing of blood vessels in the lungs.
12.1 周五 (HealthDay News)— 近期研究结果表示，吸入性伊洛前列素和波生坦此二药的联合治疗可改善病人的肺动脉高压（PAH）症状—以累进性狭窄的肺血管为病症的令人虚弱的潜在性不治之症。 1. of the University of Michigan Medical Center
密歇根州医疗中心大学 你所译得不错！！！ 谢谢指导
我会更加改进
努力！！！ 不错啊，要是每月都有，那更好 不错啊，我们的课题也有关PAH动物模型方面的。 我收藏了，谢谢！ [标签:content1][标签:content2]
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作者:admin@医学,生命科学 2011-05-24 05:14
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