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【今日新闻编译】GenoMed 发现两种与常见癌症相关
第一个基因与DNA复制有关，与胰腺癌和卵巢癌特异相关，众所周知这两种癌症在早期难以诊断。该基因有助于高危人群的早期诊断，也可以作为治疗这些难以治愈疾病的药物靶点。
第二种基因编码细胞中与蛋白质网格形成有关的成瘤蛋白质。与六种普通癌症（肺癌、结肠癌、乳腺癌。前列腺癌，卵巢癌和胰腺癌）相关，可能导致新的广谱抗肿瘤药物的产生。
Dr. David Moskowitz，GenoMed的CEO和首席医药干事说：“我们还需要对最初结果进行验证。最好的消息是我们探索新的治病基因的平台已经建立并开始运作。我们实验室现在每周测试一到两种基因，很快就可以通过我们的合作伙伴Genome Quebec一次测试数以万记的基因。
原文部分：
GenoMed Finds Two Genes Linked to Common Cancers
14 Jan 2005
GenoMed, Inc, a Next Generation DM(TM) (Disease Management) company which finds disease-causing genes in order to improve patient outcomes, announced today that it has filed a patent application on two genes linked to common cancers. These are the first new disease genes the company has filed on since its multiple patent applications about ACE, a "master" disease gene.
The first gene, involved in copying DNA, was linked specifically to pancreatic and ovarian cancers, which are notoriously hard to diagnose at an early stage. It could help in the early diagnosis of patients at high risk for these cancers, as well as serve as a possible drug target for treatment of these poorly treatable diseases.
The second gene codes for a scaffolding protein involved in building protein networks inside the cell. It was linked to all six common cancers (lung, colon, breast, prostate, ovarian, and pancreatic), and may lead to new broad-spectrum chemotherapeutic agents.
Said Dr. David Moskowitz, GenoMed's CEO and Chief Medical Officer, "We still have to validate our initial results. The best news is that our conveyor belt for finding new disease genes is up and running. We're now testing one or two genes a week in our own lab, and will soon be testing tens of thousands of genes at a time through our collaboration with Genome Quebec."
http://www.medicalnewstoday.com/medicalnews.php?newsid=18873 不错！ [标签:content1][标签:content2]
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作者:admin@医学,生命科学 2011-04-07 17:17
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